角膜缘青少年黄色肉芽肿
Juvenile xanthogranuloma of the corneoscleral limbus.
作者信息
Lim-I-Linn Zena, Li Lim
机构信息
Cornea Service, Singapore National Eye Centre, Singapore 168751.
出版信息
Cornea. 2005 Aug;24(6):745-7. doi: 10.1097/01.ico.0000154383.97989.81.
PURPOSE
To report an 11-year-old Chinese girl with juvenile xanthogranuloma of the limbus, occurring in isolation without dermatologic involvement, and to discuss the clinical and histologic features, pathogenesis, and treatment of juvenile xanthogranuloma.
METHODS
Case report and review of medical literature.
RESULTS
A total excision and biopsy of the limbal lesion with lamellar graft was performed. Histologic examination showed a xanthogranuloma. At 12-month follow-up, there was no recurrence of tumor.
CONCLUSION
The diagnosis of juvenile xanthogranuloma may be straightforward in cases that have concomitant cutaneous manifestations. However, in isolated ocular forms, histopathological examination is necessary. Unlike the more common iris lesions that are preferably treated nonsurgically, limbal lesions require surgical excision.
目的
报告一名11岁中国女孩患角膜缘幼年性黄色肉芽肿，该病例为孤立性发病，无皮肤受累情况，并探讨幼年性黄色肉芽肿的临床及组织学特征、发病机制和治疗方法。
方法
病例报告及医学文献回顾。
结果
对角膜缘病变进行了包括板层移植的完整切除及活检。组织学检查显示为黄色肉芽肿。随访12个月时，肿瘤无复发。
结论
伴有皮肤表现的幼年性黄色肉芽肿病例诊断可能较为直接。然而，对于孤立性眼部病变，组织病理学检查是必要的。与更常见的虹膜病变最好采用非手术治疗不同，角膜缘病变需要手术切除。
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