Fendrick A M, de Pouvourville G, Bitker C, Pelletier G
Ecole Polytechnique and Assistance, Publique-Hôpitaux de Paris.
Int J Technol Assess Health Care. 1992 Winter;8(1):166-84. doi: 10.1017/s0266462300008023.
To determine the potential role of extracorporeal shock wave lithotripsy (ESWL) in the treatment of symptomatic gallstone patients in France, a simulation model evaluated the health and economic effects of three different treatment strategies. Decision analysis of conventional cholecystectomy alone and either of two strategies using a combination of biliary lithotripsy and conventional cholecystectomy reveals that a strategy employing biliary ESWL results in a significant number of successfully treated patients, thus avoiding the risks and costs of abdominal surgery. Moreover, cost analysis shows that expanding the use of lithotripsy to all patients for whom the procedure is indicated increases the average cost per successfully treated patient, but, more importantly, decreases the overall costs incurred by the cohort. From a societal viewpoint, a policy using biliary ESWL in appropriate patients is superior to one of cholecystectomy alone, from both clinical and economic perspectives.
为确定体外冲击波碎石术(ESWL)在法国有症状胆结石患者治疗中的潜在作用,一个模拟模型评估了三种不同治疗策略的健康和经济影响。单独常规胆囊切除术以及使用胆道碎石术与常规胆囊切除术相结合的两种策略之一的决策分析表明,采用胆道ESWL的策略可使大量患者成功接受治疗,从而避免腹部手术的风险和成本。此外,成本分析表明,将碎石术的使用扩大到所有适合该手术的患者,会增加每位成功治疗患者的平均成本,但更重要的是,会降低该队列产生的总体成本。从社会角度来看,在合适患者中使用胆道ESWL的政策,从临床和经济角度而言,都优于仅采用胆囊切除术的政策。