Goodwin Renee D, Lewinsohn Peter M, Seeley John R
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA.
Biol Psychiatry. 2005 Nov 1;58(9):686-93. doi: 10.1016/j.biopsych.2005.04.042. Epub 2005 Jul 12.
The goal of the current study is to examine the association between cigarette smoking and panic attacks and panic disorder among youth and to investigate parental anxiety disorders and parental cigarette smoking in these links.
Data were drawn from the Oregon Adolescent Depression Project (OADP) (n = 1709). Cigarette smoking and panic attacks and panic disorder were assessed at three time points from adolescence to young adulthood.
Daily cigarette smoking at Time 1 was associated with a significantly increased risk of panic attacks (odds ratio [OR] = 2.6 [1.3, 5.3]) and panic disorder (OR = 4.2 [2.0, 8.9]) at Time 3. After adjusting for parental anxiety disorder and parental smoking, the association between cigarette smoking and panic attack was no longer statistically significant (OR = 2.0 [.9, 4.5]), though the association between cigarette smoking and panic disorder remained (OR = 3.7 [1.6, 8.9]). The association between smoking and panic was not evident between smoking and other anxiety disorders.
These findings replicate previous results showing cigarette smoking in adolescence is associated with an increased risk of panic attacks and panic disorder in early adulthood and provide initial evidence that parental anxiety and parental smoking may play a role.
本研究的目的是探讨青少年吸烟与惊恐发作及惊恐障碍之间的关联，并调查这些关联中父母的焦虑症和父母吸烟情况。
数据取自俄勒冈青少年抑郁症项目（OADP）（n = 1709）。从青春期到青年期的三个时间点对吸烟、惊恐发作和惊恐障碍进行了评估。
第1时间点的每日吸烟与第3时间点惊恐发作（优势比[OR]=2.6[1.3,5.3]）和惊恐障碍（OR = 4.2[2.0,8.9]）的风险显著增加相关。在对父母焦虑症和父母吸烟进行调整后，吸烟与惊恐发作之间的关联不再具有统计学意义（OR = 2.0[.9,4.5]），尽管吸烟与惊恐障碍之间的关联仍然存在（OR = 3.7[1.6,8.9]）。吸烟与其他焦虑症之间未发现吸烟与惊恐之间的关联。
这些发现重复了先前的结果，表明青少年吸烟与成年早期惊恐发作和惊恐障碍的风险增加有关，并提供了初步证据表明父母焦虑和父母吸烟可能起作用。
