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以大量腹水为髓外病变表现的慢性髓性白血病对甲磺酸伊马替尼治疗有反应。

Chronic myeloid leukemia presenting with extramedullary disease as massive ascites responding to imatinib mesylate.

作者信息

Aleem Aamer, Siddiqui Neelam

机构信息

Department of Medicine, Hematology/Oncology Division, King Khalid University Hospital, Riyadh, Saudi Arabia.

出版信息

Leuk Lymphoma. 2005 Jul;46(7):1097-9. doi: 10.1080/10428190500096781.

DOI:10.1080/10428190500096781
PMID:16019565
Abstract

Patients with chronic myeloid leukemia (CML) can develop extramedullary involvement during the course of the illness. This usually occurs during the accelerated phase or blast crisis. We describe a patient who presented with massive ascites probably due to mesenteric/peritoneal infiltration during chronic phase CML. There was an excellent response to imatinib with a complete cytogenetic response and total disappearance of ascites.

摘要

慢性髓性白血病（CML）患者在病程中可发生髓外浸润。这通常发生在加速期或急变期。我们描述了一名患者，在慢性期CML期间出现大量腹水，可能是由于肠系膜/腹膜浸润所致。对伊马替尼有良好反应，细胞遗传学完全缓解，腹水完全消失。

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