慢性腿部溃疡的标准化手术治疗方法。

Standardised method of surgical treatment of chronic leg ulcers.

作者信息

Bitsch Mikael, Saunte Ditte Marie, Lohmann Michael, Holstein Per E, Jørgensen Bo, Gottrup Finn

机构信息

Copenhagen Wound Healing Center, Bispebjerg Hospital, University Hospital, Denmark.

出版信息

Scand J Plast Reconstr Surg Hand Surg. 2005;39(3):162-9. doi: 10.1080/02844310510006196.

DOI:10.1080/02844310510006196

PMID:16019749

Abstract

Healing and recurrence rates were compared in leg ulcers of different aetiology in 385 patients with 406 chronic leg ulcers. Standard treatment was excision of the ulcer followed by meshed split-skin grafting and correction of superficial venous insufficiency in the area. The median age of the patients was 75 years (range 16-95). After one year 345 patients with 357 leg ulcers were alive. Overall healing rate was 64% (227 in 357 legs) after one year. The best results were achieved in traumatic ulcers (31 in 36 ulcers) and worst for the arterial ulcers (4 in 20 ulcers). Recurrence rate in venous and venous/ischaemic ulcers was 14% (33 in 235 legs) and 8% (n=3) in the traumatic ulcers. Vasculitic ulcers tend to recur 59% (n=10), but the graft does relieve pain.

摘要

对385例患有406处慢性腿部溃疡的不同病因腿部溃疡患者的愈合率和复发率进行了比较。标准治疗方法是切除溃疡，随后进行网状自体中厚皮片移植，并矫正该区域的浅静脉功能不全。患者的中位年龄为75岁（范围16 - 95岁）。一年后，345例患有357处腿部溃疡的患者存活。一年后的总体愈合率为64%（357条腿中有227条愈合）。创伤性溃疡的愈合效果最佳（36处溃疡中有31处愈合），动脉性溃疡的愈合效果最差（20处溃疡中有4处愈合）。静脉性和静脉/缺血性溃疡的复发率为14%（235条腿中有33条复发），创伤性溃疡的复发率为8%（n = 3）。血管炎性溃疡的复发率倾向于59%（n = 10），但移植确实能缓解疼痛。