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用于快速检测产毒真菌和霉菌毒素的DNA阵列、电子鼻和舌、生物传感器及受体:综述

DNA arrays, electronic noses and tongues, biosensors and receptors for rapid detection of toxigenic fungi and mycotoxins: a review.

作者信息

Logrieco A, Arrigan D W M, Brengel-Pesce K, Siciliano P, Tothill I

机构信息

Istituto di Scienze delle Produzioni Alimentari, CNR, Via Amendola 122/O, I-70126 Bari, Italy.

出版信息

Food Addit Contam. 2005 Apr;22(4):335-44. doi: 10.1080/02652030500070176.

DOI:10.1080/02652030500070176
PMID:16019803
Abstract

This paper presents an overview of how microsystem technology tools can be applied to the development of rapid, out-of-laboratory measurement capabilities for the determinations of toxigenic fungi and mycotoxins in foodstuffs. Most of the topics discussed are all under investigation within the European Commission-sponsored project Good-Food (FP6-IST). These are DNA arrays, electronic noses and electronic tongues for the detection of fungal contaminants in feed, and biosensors and chemical sensors based on microfabricated electrode systems, antibodies and novel synthetic receptors for the detection of specific mycotoxins. The approach to resolution of these difficult measurement problems in real matrices requires a multidisciplinary approach. The technology tools discussed can provide a route to the rapid, on-site generation of data that can aid the safe production of high-quality foodstuffs.

摘要

本文概述了微系统技术工具如何应用于开发快速、实验室外测量能力,以测定食品中的产毒真菌和霉菌毒素。所讨论的大多数主题都在欧盟委员会资助的项目“优质食品”(FP6-IST)中进行研究。这些主题包括用于检测饲料中真菌污染物的DNA阵列、电子鼻和电子舌,以及基于微制造电极系统、抗体和新型合成受体的生物传感器和化学传感器,用于检测特定的霉菌毒素。解决实际基质中这些困难测量问题的方法需要多学科方法。所讨论的技术工具可以提供一条途径,以快速、现场生成数据,有助于安全生产高质量食品。

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