den Hoed Irma D M, Granzen B, Granzen B, Aronson Daniel C, Pauwels Patrick, de Kraker J, van Heurn L W Ernest
Department of Paediatric Surgery, Paediatrics, and Pathology, University Hospital, Maastricht, The Netherlands.
Pediatr Hematol Oncol. 2005 Jul-Aug;22(5):387-90. doi: 10.1080/08880010590964228.
Primary angiosarcoma of the spleen is rare and the prognosis is very poor. The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma. At diagnosis there were liver metastases. After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection. She remained in complete remission over 2 years from diagnosis.
脾脏原发性血管肉瘤罕见，预后很差。作者报告了一名2岁女童，其脾脏血管肉瘤发生自发性破裂。诊断时已有肝转移。脾切除术后，她接受了异环磷酰胺、长春新碱和放线菌素D联合化疗，并进行了部分肝切除。自诊断以来，她已完全缓解超过2年。
