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变应性肉芽肿性血管炎中的孤立性动眼神经麻痹。

Isolated oculomotor nerve palsy in Churg-Strauss syndrome.

作者信息

Tsuda Hiromasa, Ishikawa Hiroshi, Majima Toru, Sawada Umihiko, Mizutani Tomohiko

机构信息

Division of Neurology, Nihon University, School of Medicine, Oyaguchikamicho, Tokyo.

出版信息

Intern Med. 2005 Jun;44(6):638-40. doi: 10.2169/internalmedicine.44.638.

Abstract

A 30-year-old man with bronchial asthma complained of horizontal diplopia. Partial oculomotor nerve palsy with restrictions of elevation and adduction, and mydriasis was observed in the left eye. Cranial magnetic resonance imaging demonstrated an infarct lesion in the territory of the left superior median mesencephalic branch of the posterior cerebral artery. Based on bronchial asthma, hypereosinophilia, mononeuropathy multiplex, pulmonary eosinophilia and positive perinuclear antineutrophil cytoplasmic antibody in the serum, the patient was diagnosed as having Churg-Strauss syndrome. This is the first case of oculomotor nerve palsy due to midbrain infarction associated with Churg-Strauss syndrome.

摘要

一名30岁支气管哮喘男性患者主诉水平复视。左眼出现部分动眼神经麻痹,伴有上抬和内收受限以及瞳孔散大。头颅磁共振成像显示大脑后动脉左中脑上正中分支供血区域有梗死灶。基于支气管哮喘、嗜酸性粒细胞增多、多发性单神经病、肺部嗜酸性粒细胞浸润以及血清中核周型抗中性粒细胞胞浆抗体阳性,该患者被诊断为变应性肉芽肿性血管炎(Churg-Strauss综合征)。这是首例与变应性肉芽肿性血管炎相关的中脑梗死所致动眼神经麻痹病例。

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