一名抗中性粒细胞胞浆抗体（ANCA）阴性的变应性肉芽肿性血管炎（Churg-Strauss综合征）患者发生视网膜中央动脉阻塞。
Central retinal artery occlusion in an ANCA negative Churg-Strauss syndrome patient.
作者信息
Türkçüoğlu Peykan, Isik Ahmet, Deniz Nurettin, Turgut Burak, Kan Elif Kiliç
机构信息
Department of Ophthalmology, Firat University School of Medicine, Elaziğ, Turkey.
出版信息
Int Ophthalmol. 2007 Dec;27(6):369-71. doi: 10.1007/s10792-007-9084-3. Epub 2007 May 24.
PURPOSE
To describe a central retinal artery occlusion in a patient with antineutrophil cytoplasmic antibody (ANCA) negative Churg-Strauss syndrome.
METHODS
Review of clinical and laboratory findings of a 44-year-old woman with ANCA negative Churg-Strauss syndrome that developed sudden vision loss in left eye.
RESULTS
Left central retinal artery occlusion was diagnosed by retinal whitening, a cherry-red spot, and delayed arterial filling on fluorescein angiography. Perinuclear ANCA and cytoplasmic ANCA were negative.
CONCLUSION
Central retinal artery occlusion can occur in ANCA negative Churg-Strauss syndrome. Patients with this diagnosis should be considered for prophylactic high dose corticosteroid, regardless of their ANCA status.
目的
描述1例抗中性粒细胞胞浆抗体（ANCA）阴性的Churg-Strauss综合征患者发生的视网膜中央动脉阻塞。
方法
回顾1例44岁ANCA阴性的Churg-Strauss综合征女性患者的临床和实验室检查结果，该患者左眼突然失明。
结果
通过视网膜变白、樱桃红斑以及荧光素血管造影显示动脉充盈延迟，诊断为左眼视网膜中央动脉阻塞。核周型ANCA和胞浆型ANCA均为阴性。
结论
ANCA阴性的Churg-Strauss综合征可发生视网膜中央动脉阻塞。无论ANCA状态如何，对于诊断为此病的患者均应考虑给予预防性高剂量皮质类固醇治疗。
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