Lefante John J, Harmon Gary N, Ashby Keith M, Barnard David, Webber Larry S
Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Qual Life Res. 2005 Apr;14(3):665-73. doi: 10.1007/s11136-004-0784-0.
The utility of the SF-8 for assessing health-related quality of life (HRQL) is demonstrated. Race and gender differences in physical component (PCS) and mental component (MCS) summary scores among participants in the CENLA Medication Access Program (CMAP), along with comparisons to the United States population are made.
Age-adjusted multiple linear regression analyses were used to compare 1687 CMAP participants to the US population. Internal race and gender comparisons, adjusting for age and the number of self reported diagnoses, were also obtained. The paired t-test was used to assess 6-month change in PCS and MCS scores for a subset of 342 participants.
CMAP participants have PCS and MCS scores that are significantly 10-12 points lower than the US population, indicating lower self-reported HRQL. Females have significantly higher PCS and significantly lower MCS than males. African-Americans have significantly higher MCS than Caucasians. Significant increases in both PCS and MCS were observed for the subset of participants after 6 months of intervention.
The expected lower baseline PCS and MCS measures and the expected associations with age and number of diagnoses indicate that the SF-8 survey is an effective tool for measuring the HRQL of participants in this program. Preliminary results indicate significant increases in both PCS and MCS 6 months after intervention.
证明SF-8在评估健康相关生活质量(HRQL)方面的效用。对中美洲药物获取计划(CMAP)参与者的身体成分(PCS)和心理成分(MCS)总结得分中的种族和性别差异进行分析,并与美国人群进行比较。
采用年龄调整后的多元线性回归分析,将1687名CMAP参与者与美国人群进行比较。还进行了内部种族和性别比较,并对年龄和自我报告的诊断数量进行了调整。使用配对t检验评估342名参与者子集中PCS和MCS得分的6个月变化。
CMAP参与者的PCS和MCS得分比美国人群显著低10 - 12分,表明自我报告的HRQL较低。女性的PCS显著高于男性,而MCS显著低于男性。非裔美国人的MCS显著高于白种人。干预6个月后,参与者子集中的PCS和MCS均有显著增加。
预期较低水平的基线PCS和MCS测量值以及与年龄和诊断数量的预期关联表明,SF-8调查是测量该计划参与者HRQL的有效工具。初步结果表明,干预6个月后,PCS和MCS均有显著增加。