Soto María, Failde Inmaculada, Márquez Soledad, Benítez Encarnación, Ramos Ignacio, Barba Antonio, López Fernando
Hospital Universitario Puerta del Mar de Cádiz, Servicio de Medicina Preventiva, Spain.
Qual Life Res. 2005 Apr;14(3):759-68. doi: 10.1007/pl00022069.
The aim of the study was to determine the clinical and sociodemographic factors related to the physical and mental components of the health-related quality of life (HRQL) in coronary patients.
We studied 132 patients diagnosed with Acute Myocardial Infarction (AMI) and unstable angina admitted to a cardiology unit over a period of 18 months. The HRQL was assessed with the Short Form 36 Health Questionnaire (SF-36) and the presence of possible mental disorders was measured using the General Health Questionnaire (GHQ-28). In order to study the variables related to both physical and mental summary components of the SF-36, two multiple linear regression models were constructed with the physical (PCS) and the mental component summary (MCS) as outcome variables.
The GHQ-28 score > or = 6 was the variable most associated with the lowest PCS in the patients studied. Moreover in the patients with a personal history of coronary heart disease (CHD), age tended to increase the PCS of the HRQL, whereas in those with no such history, age diminished the PCS score. For the MCS, not being married, being of female sex, having GHQ-28 scores > or = 6 and being of younger age were the four variables most related to the lowest MCS score in the patients studied.
Age, sex, marital status, personal history of CHD and the presence of a possible mental disorder were the factors most related to HRQL in the coronary patients studied. Focusing medical attention on these groups could contribute to improving their quality of life.
本研究旨在确定与冠心病患者健康相关生活质量(HRQL)的身体和心理成分相关的临床及社会人口学因素。
我们研究了在18个月期间入住心内科的132例诊断为急性心肌梗死(AMI)和不稳定型心绞痛的患者。使用简短健康调查问卷(SF-36)评估HRQL,并使用一般健康问卷(GHQ-28)测量是否存在可能的精神障碍。为了研究与SF-36的身体和心理总结成分相关的变量,构建了两个多元线性回归模型,将身体成分总结(PCS)和心理成分总结(MCS)作为结果变量。
在研究的患者中,GHQ-28评分≥6是与最低PCS最相关的变量。此外,有冠心病(CHD)个人病史的患者,年龄倾向于增加HRQL的PCS,而无此类病史的患者,年龄会降低PCS评分。对于MCS,未婚、女性、GHQ-28评分≥6和年龄较小是研究患者中与最低MCS评分最相关的四个变量。
年龄、性别、婚姻状况、CHD个人病史以及可能存在的精神障碍是所研究冠心病患者中与HRQL最相关的因素。关注这些人群的医疗问题有助于改善他们的生活质量。