Sandalov Iu G, Glebov R N, Kryzhanovskii G N
Biull Eksp Biol Med. 1979 Sep;88(9):291-4.
It was shown that Mg-ATP increased light diffusion in the suspension of synaptic vesicles (SV) of the rat brain in the presence of actinolike protein (ALP) of the bovine brain (the superprecipitation test). ALP enhanced the activity of the SV Mg-ATPase and increased endogenic moradrenaline release from the bovine hypothalamus SV, eliminated by cutochalazine B. Glycolipids (gengliosides and cerebrosides) inhibited the superprecipitation test. The results are considered from the standpoint of a contractile hypothesis on the mediator secretion.
结果表明,在牛脑肌动蛋白样蛋白(ALP)存在的情况下,Mg-ATP可增加大鼠脑突触小泡(SV)悬浮液中的光扩散(超沉淀试验)。ALP增强了SV Mg-ATP酶的活性,并增加了牛下丘脑SV内源性去甲肾上腺素的释放,而这一释放被布他拉嗪B所消除。糖脂(神经节苷脂和脑苷脂)抑制了超沉淀试验。从介质分泌的收缩假说角度对这些结果进行了考量。