[Effect of several tropane derivatives on noradrenaline absorption by hypothalamic synaptic vesicles].

The influence of some tropan derivatives on the absorption of exogenous norepinephrine was studied in experiments on the isolated synaptic vesicles of the hypothalamus. LK II (beta-morpholinopropionic acid tropine ester dihydrochloride) at the concentration of 1. -5M decreased (like cocaine) the passive consumption of norephinephrine. The dependence of this effect on the transmitter concentration in the incubation medium was demonstrated.