Epigenetic drift in aging identical twins.
作者信息
Martin George M
机构信息
Department of Pathology, University of Washington, Seattle, WA 98195, USA.
出版信息
Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10413-4. doi: 10.1073/pnas.0504743102. Epub 2005 Jul 18.
Abstract
摘要
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本文引用的文献
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Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10604-9. doi: 10.1073/pnas.0500398102. Epub 2005 Jul 11.
2
Identification of hundreds of conserved and nonconserved human microRNAs.数百种保守和非保守人类微小RNA的鉴定。
Nat Genet. 2005 Jul;37(7):766-70. doi: 10.1038/ng1590. Epub 2005 Jun 19.
3
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Nature. 2005 Jun 16;435(7044):903-10. doi: 10.1038/nature03663.
4
Segmental duplications and copy-number variation in the human genome.人类基因组中的节段性重复和拷贝数变异
Am J Hum Genet. 2005 Jul;77(1):78-88. doi: 10.1086/431652. Epub 2005 May 25.
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