Farmer D L
Department of Surgery, Fetal Treatment Program, Children's Hospital of Michigan, 3901 Beaubien Blvd., Detroit, MI 48201, USA.
Pediatr Radiol. 1998 Jun;28(6):409-13. doi: 10.1007/s002470050372.
Fetal therapy is a logical extension of fetal diagnosis. Fetal surgery has been performed in humans for the past 10 years. During this time, technical obstacles have been overcome and the natural history of many fetal disorders has been defined. A select group of disorders amenable to potential improvement by fetal treatment has been identified including fetal urinary tract obstruction, fetal diaphragmatic hernia, fetal congenital cystic adenomatoid malformation and fetal sacrococcygeal teratoma. The fetal surgical experience with each of these lesions is reviewed and the maternal risk of fetal surgery is discussed.
胎儿治疗是胎儿诊断的合理延伸。在过去十年中,人类已开展了胎儿手术。在此期间,技术障碍已被克服,许多胎儿疾病的自然病史也已明确。已确定了一组有望通过胎儿治疗得到改善的特定疾病,包括胎儿尿路梗阻、胎儿膈疝、胎儿先天性囊性腺瘤样畸形和胎儿骶尾部畸胎瘤。本文回顾了针对每种此类病变的胎儿手术经验,并讨论了胎儿手术对母亲的风险。