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[青光眼与角膜厚度的风险]

[The risk of glaucoma and corneal thickness].

作者信息

Böhm A G

机构信息

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Carl Gustav Carus, Dresden.

出版信息

Ophthalmologe. 2005 Sep;102(9):909-16; quiz 917. doi: 10.1007/s00347-005-1248-9.

Abstract

Intraocular pressure is still the most important risk factor for the development of glaucomatous optic nerve damage. There is growing evidence that corneal thickness is a risk factor for the development of glaucoma. This might be caused by the effect of corneal thickness on intraocular pressure (IOP) measurements. Goldmann applanation tonometry measurements are correlated with corneal thickness. Thick corneas lead to false high readings whereas thin corneas lead to false low readings. If corneal thickness as a risk factor for glaucoma is only related to the dependency of IOP measurements on corneal thickness or is related to possible different biomechanical tissue properties in glaucomatous eyes is not known. However, a large proportion of the corneal thickness effect seems to be related to the effect on IOP readings by applanation tonometry. Neglecting corneal thickness can lead to false measurements of IOP with consequent misdiagnosis and false treatment. Therefore, measurements of corneal thickness should be performed in glaucoma patients and suspects.

摘要

眼压仍然是青光眼性视神经损伤发生的最重要风险因素。越来越多的证据表明,角膜厚度是青光眼发生的一个风险因素。这可能是由角膜厚度对眼压测量的影响所致。Goldmann压平眼压测量值与角膜厚度相关。厚角膜会导致读数假性偏高,而薄角膜会导致读数假性偏低。角膜厚度作为青光眼的一个风险因素,是否仅与眼压测量对角膜厚度的依赖性有关,或者是否与青光眼患者眼睛可能存在的不同生物力学组织特性有关,目前尚不清楚。然而,角膜厚度效应的很大一部分似乎与压平眼压计对眼压读数的影响有关。忽略角膜厚度会导致眼压测量错误,进而导致误诊和错误治疗。因此,青光眼患者和疑似患者应进行角膜厚度测量。

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