中国彝族群体11个Y染色体短串联重复序列单倍型的基因多态性
Genetic polymorphisms for 11 Y-STRs haplotypes of Chinese Yi ethnic minority group.
作者信息
Zhu Bofeng, Shen Chunmei, Qian Guangli, Shi Ruiyi, Dang Yonghui, Zhu Jun, Huang Ping, Xu Yongcheng, Zhao Qianzi, Ma Jun, Liu Yao
机构信息
The Key Laboratory of Environment and Gene Related to Diseases, Ministry of Education, Xi'an Jiaotong University, Shaanxi 710061, China.
出版信息
Forensic Sci Int. 2006 May 10;158(2-3):229-33. doi: 10.1016/j.forsciint.2005.05.031. Epub 2005 Jul 18.
Eleven Y-STRs loci including minimal haplotypes (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, and DYS385a,b) and two additional loci, namely DYS438 and DYS439 have been co-amplified in 100 healthy unrelated males of Chinese Yi minority ethnic group using the Y-PLEX 5 and Y-PLEX 6 kit, in order to investigate allele and haplotype frequencies of Yi population, evaluate their usefulness in forensic paternity testing and human identification, and enrich Chinese population genetic informational resources. Out of a total of 100 individuals 85 showed different haplotypes, while 8 haplotypes occurred more than once. The overall haplotype diversity for 11 Y-STRs loci was 0.9945.
利用Y-PLEX 5和Y-PLEX 6试剂盒，在中国彝族100名健康无关男性中对11个Y-STR基因座（包括最小单倍型DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393以及DYS385a、b）和另外两个基因座DYS438和DYS439进行了复合扩增，以研究彝族人群的等位基因和单倍型频率，评估它们在法医亲子鉴定和个体识别中的实用性，并丰富中国人群遗传信息资源。在总共100个个体中，85个呈现不同的单倍型，而有8种单倍型出现不止一次。11个Y-STR基因座的总体单倍型多样性为0.9945。
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