中国纳西族群体中的12个Y染色体短串联重复序列单倍型
12 Y-STRs haplotypes in Chinese Naxi ethnic minority group.
作者信息
Xin Na, Chen Teng, Yu Bing, Li Shengbin
机构信息
Department of Forensic Science, Medical College of Xi'an Jiaotong University, Xi'an 710061, PR China.
出版信息
Forensic Sci Int. 2008 Jan 30;174(2-3):244-8. doi: 10.1016/j.forsciint.2007.03.021. Epub 2007 May 25.
Twelve Y-STRs loci including minimal haplotypes (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, and DYS385a,b) and three additional loci, namely DYS437, DYS438 and DYS439 were co-amplified in 138 healthy unrelated males of Chinese Naxi ethnic minority group using the PowerPlex Y System. A total of 113 haplotypes were identified, among which 103 were unique, and 6, 2, 1 and 1 were found in 2, 4, 5 and 10 individuals, respectively. The haplotype diversity for 12 Y-STRs loci was 0.9923.The results from the present study can be used in forensic application and population genetics in the region, and can enrich Chinese ethnical genetic informational resources.
利用PowerPlex Y系统，在中国纳西族138名健康无关男性中对12个Y-STR基因座进行共扩增，这些基因座包括最小单倍型（DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393和DYS385a,b）以及另外3个基因座，即DYS437、DYS438和DYS439。共鉴定出113种单倍型，其中103种是独特的，分别在2、4、5和10个人中发现了6种、2种、1种和1种单倍型。12个Y-STR基因座的单倍型多样性为0.9923。本研究结果可用于该地区的法医学应用和群体遗传学研究，并可丰富中国民族遗传信息资源。
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