van de Weijgert E J, Braun J J
Department of Internal Medicine, Schieland Hospital, Schiedam, Netherlands.
Neth J Med. 1992 Apr;40(3-4):175-82.
In 40 subjects (23 treated with antihypertensive medication), 24-h ambulatory blood pressure was measured with an oscillometric blood pressure monitor (Spacelabs model 90202). We studied applicability in the out-patient department with regard to patient tolerance, correlation with mercury manometer measurements, 24-h blood pressure variability and the use in detecting "white-coat" hypertension. The measurements were tolerated quite well except for complaints of sleep disturbance and local irritation from the cuff. The average percentage of missed measuring points was 9.2%. Correlation between blood pressure with the mercury manometer and the Spacelabs monitor (averages of three consecutive readings) was: systolic 0.87 and diastolic 0.73 (P less than 0.001). No evidence for systematic error between the two methods was found. Diurnal blood pressure variation was significant with an average night-time drop of 12 +/- 15 mmHg systolic and 12 +/- 11 mmHg diastolic. "Office" blood pressure measured with the Spacelabs monitor was in the hypertensive range for 28 patients (systolic greater than or equal to 160 and/or diastolic greater than or equal to 95 mmHg). Only 15 of these subjects still met the hypertension criteria on the basis of mean daytime ambulatory blood pressure values. When ambulatory blood pressures during arbitrary 3-h periods of the daytime were studied, the number of patients with established hypertension did not change. The patients with this "office" or "white-coat" hypertensive response could not be distinguished on the basis of variability in daytime blood pressure.(ABSTRACT TRUNCATED AT 250 WORDS)
在40名受试者(23名接受抗高血压药物治疗)中,使用示波血压监测仪(Spacelabs 90202型)测量24小时动态血压。我们研究了其在门诊中的适用性,涉及患者耐受性、与汞柱式血压计测量值的相关性、24小时血压变异性以及检测“白大衣”高血压的用途。除了有睡眠障碍和袖带局部刺激的主诉外,测量耐受性良好。测量点遗漏的平均百分比为9.2%。汞柱式血压计与Spacelabs监测仪(连续三次读数的平均值)之间血压的相关性为:收缩压0.87,舒张压0.73(P<0.001)。未发现两种方法之间存在系统误差。昼夜血压变化显著,收缩压平均夜间下降12±15 mmHg,舒张压平均夜间下降12±11 mmHg。用Spacelabs监测仪测量的“诊室”血压在28名患者中处于高血压范围(收缩压≥160和/或舒张压≥95 mmHg)。这些受试者中只有15名根据日间动态血压平均值仍符合高血压标准。当研究白天任意3小时期间的动态血压时,确诊高血压的患者数量没有变化。根据白天血压变异性无法区分有这种“诊室”或“白大衣”高血压反应的患者。(摘要截短至250字)