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德国的职业性阻塞性气道疾病:国际比较中的发病率及病因

Occupational obstructive airway diseases in Germany: Frequency and causes in an international comparison.

作者信息

Latza Ute, Baur Xaver

机构信息

Institute for Occupational Medicine, University of Hamburg, Hamburg State Department for Science and Health, Germany.

出版信息

Am J Ind Med. 2005 Aug;48(2):144-52. doi: 10.1002/ajim.20186.

Abstract

BACKGROUND

Occupational inhalative exposures contribute to a significant proportion of obstructive airway diseases (OAD), namely chronic obstructive pulmonary disease (COPD) and asthma.

METHODS

The number of occupational OAD in the German industrial sector for the year 2003 are presented. Other analyses of surveillance data were retrieved from Medline.

RESULTS

Most confirmed reports of OAD are cases of sensitizer induced occupational asthma (625 confirmed cases) followed by COPD in coal miners (414 cases), irritant induced occupational asthma (156 cases), and isocyanate asthma (54 cases). Main causes of occupational asthma in Germany comprise flour/flour constituents (35.9%), food/feed dust (9.0%), and isocyanates (6.5%). Flour and grain dust is a frequent cause of occupational asthma in most European countries and South Africa. Isocyanates are still a problem worldwide.

CONCLUSIONS

Although wide differences in the estimated incidences between countries exist due to deficits in the coverage of occupational OAD, the high numbers necessitate improvement of preventive measures.

摘要

背景

职业性吸入暴露在阻塞性气道疾病(OAD)中占很大比例,即慢性阻塞性肺疾病(COPD)和哮喘。

方法

列出了2003年德国工业部门职业性OAD的数量。从医学在线数据库检索了其他监测数据分析。

结果

大多数确诊的OAD报告是致敏剂诱发的职业性哮喘病例(625例确诊病例),其次是煤矿工人中的COPD(414例)、刺激性诱发的职业性哮喘(156例)和异氰酸酯哮喘(54例)。德国职业性哮喘的主要病因包括面粉/面粉成分(35.9%)、食品/饲料粉尘(9.0%)和异氰酸酯(6.5%)。面粉和谷物粉尘是大多数欧洲国家和南非职业性哮喘的常见病因。异氰酸酯在全球范围内仍然是一个问题。

结论

尽管由于职业性OAD覆盖范围的不足,各国估计发病率存在很大差异,但如此高的发病数量仍需要改进预防措施。

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