Kwok L Stephen, Pierscionek Barbara K, Bullimore Mark, Swarbrick Helen A, Mountford John, Sutton Gerard
Department of Ophthalmology, Prince of Wales Hospital, The University of New South Wales, Sydney, New South Wales, Australia.
Clin Exp Ophthalmol. 2005 Aug;33(4):343-7. doi: 10.1111/j.1442-9071.2005.01059.x.
Orthokeratology attempts to reduce myopia by remoulding the corneal shape with contact lenses. A recent resurgence is predicated on new contact lens designs with a prefigured back contact surface and higher oxygen transmissibility. This Clinical Controversy presents an analysis of the risk factors associated with orthokeratology and its suitability for children, followed by commentaries from specialists who have an interest in the method. Some state that there is a lack of data on relative risks of corneal infection and that there is a need for large-scale randomized controlled studies; however, opinion is expressed by others that orthokeratology is a clinically safe procedure using modern lenses. It is noted that the physiological and biophysical bases of orthokeratology are virtually unknown, and further research on the human cornea is indicated to scientifically establish the safety of orthokeratology. Prospective patients, and their parents in the case of children, should be fully informed of the risks.
角膜塑形术试图通过使用隐形眼镜重塑角膜形状来降低近视。最近的复兴基于具有预先设计的后表面和更高透氧性的新型隐形眼镜设计。这一临床争议对与角膜塑形术相关的风险因素及其对儿童的适用性进行了分析，随后是对该方法感兴趣的专家的评论。一些人指出，缺乏关于角膜感染相对风险的数据，需要进行大规模随机对照研究；然而，其他人则认为，使用现代镜片的角膜塑形术是一种临床安全的手术。需要注意的是，角膜塑形术的生理和生物物理基础几乎未知，需要对人类角膜进行进一步研究，以科学地确定角膜塑形术的安全性。潜在患者以及儿童患者的父母应充分了解风险。
