Walline Jeffrey J, Holden Brien A, Bullimore Mark A, Rah Marjorie J, Asbell Penny A, Barr Joseph T, Caroline Patrick J, Cavanagh H Dwight, Despotidis Nick, Desmond Fonn, Koffler Bruce H, Reeder Kevin, Swarbrick Helen A, Wohl Lisa G
The Ohio State University College of Optometry, The Vision Cooperative Research Centre, OH, USA.
Eye Contact Lens. 2005 Sep;31(5):209-14. doi: 10.1097/01.icl.0000179709.76832.4f.
The application of contact lenses to alter the shape of the cornea and temporarily reduce or eliminate myopia is known as orthokeratology, corneal refractive therapy, or corneal reshaping. It was first introduced in the 1960s, but high oxygen permeable materials and more sophisticated designs allow patients to wear contact lenses only during sleep, while dramatically improving the predictability and rate of myopia reduction. Many studies have shown that most corneal reshaping patients achieve uncorrected visual acuity of 20/25 or better that lasts all day long in one to two weeks of nighttime wear. Treatment is primarily effective through central epithelial thinning and midperipheral epithelial and stromal thickening. Much remains to be learned about corneal reshaping contact lenses and their effects on the cornea.
The authors reviewed existing knowledge and determined what needs to be learned in order to provide patients with appropriate informed consent prior to corneal reshaping contact lens wear.
While corneal reshaping contact lenses are effective at temporarily reducing or eliminating myopia, claims about the progress of myopia being controlled with corneal reshaping contact lenses should not be made until further studies are published in peer-reviewed literature. The incidence and prevalence of microbial keratitis related to corneal reshaping contact lens wear is not known. Any overnight wear of contact lenses increases the risk of infection, but it is not known whether the risks of microbial keratitis are greater for corneal reshaping overnight contact lens wearers than other form of overnight contact lens wear. It is also not known whether the risk of microbial keratitis is greater for children than adults, but we must determine if children are at greater risk than adults because many children are wearing corneal reshaping contact lenses.
Finally, it is recommended that ongoing education be provided to practitioners and staff regarding safety, informed consent, and prevention of potential problems, with special emphasis on the critical need to properly and thoroughly disinfect lenses that will be worn overnight.
应用隐形眼镜改变角膜形状并暂时降低或消除近视,这被称为角膜塑形术、角膜屈光治疗或角膜重塑。它于20世纪60年代首次引入,但高透氧材料和更精密的设计使患者只需在睡眠期间佩戴隐形眼镜,同时显著提高了近视降低的可预测性和速率。许多研究表明,大多数角膜重塑患者在夜间佩戴一到两周后可实现全天无需矫正视力达到20/25或更好。该治疗主要通过中央上皮变薄以及中周边上皮和基质增厚起作用。关于角膜重塑隐形眼镜及其对角膜的影响,仍有许多有待了解的地方。
作者回顾了现有知识,并确定在角膜重塑隐形眼镜佩戴前为患者提供适当的知情同意需要了解哪些内容。
虽然角膜重塑隐形眼镜在暂时降低或消除近视方面有效,但在同行评审文献发表进一步研究之前,不应声称角膜重塑隐形眼镜能控制近视进展。与角膜重塑隐形眼镜佩戴相关的微生物性角膜炎的发病率和患病率尚不清楚。任何隐形眼镜过夜佩戴都会增加感染风险,但尚不清楚角膜重塑过夜隐形眼镜佩戴者发生微生物性角膜炎的风险是否高于其他形式的过夜隐形眼镜佩戴者。也不清楚儿童发生微生物性角膜炎的风险是否高于成人,但我们必须确定儿童是否比成人风险更大,因为许多儿童正在佩戴角膜重塑隐形眼镜。
最后,建议持续对从业者和工作人员进行关于安全、知情同意以及潜在问题预防的教育,特别强调正确彻底消毒过夜佩戴的镜片的迫切需求。