Sharma Vinod K, Sethuraman Gomathy, Bhat Radhakrishna
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Contact Dermatitis. 2005 Aug;53(2):84-8. doi: 10.1111/j.0105-1873.2005.00652.x.
Our aim was to study the evolution of clinical pattern of parthenium dermatitis. Patients with clinical picture consistent with parthenium dermatitis for 3 years or more along with positive patch test to parthenium were studied. Patients were questioned regarding the site(s) of dermatitis at the onset and change in localization in the following years. Patients were classified into airborne contact dermatitis, chronic actinic dermatitis (CAD) pattern or mixed pattern dermatitis. There were 74 patients (49 men and 25 women) with an age range of 22-70 years and the mean duration of 7.7 years. 60 (39 men and 21 women) patients had airborne contact dermatitis, 5 mixed pattern and 9 CAD pattern at the onset. Of the 60 patients with airborne contact dermatitis, 27 (19 men and 8 women) changed to CAD pattern and 11 (6 men and 5 women) to mixed pattern after an average period of 4.2 years. Of the 19 patients photopatch-tested with parthenium, 3 showed photoallergic reaction and the other 3 showed photoaggravation. Our results suggest that the clinical pattern of parthenium dermatitis undergoes a significant change after the onset, i.e. progresses from airborne contact dermatitis to mixed pattern or CAD pattern.
我们的目的是研究银胶菊皮炎临床模式的演变。对临床症状符合银胶菊皮炎且病程达3年或更长时间、同时对银胶菊斑贴试验呈阳性的患者进行了研究。询问患者皮炎初发时的部位以及随后几年中部位的变化情况。将患者分为空气传播性接触性皮炎、慢性光化性皮炎（CAD）型或混合型皮炎。共有74例患者（49名男性和25名女性），年龄范围为22至70岁，平均病程为7.7年。初发时，60例（39名男性和21名女性）为空气传播性接触性皮炎，5例为混合型，9例为CAD型。在60例空气传播性接触性皮炎患者中，平均4.2年后，27例（19名男性和8名女性）转变为CAD型，11例（6名男性和5名女性）转变为混合型。在19例接受银胶菊光斑贴试验的患者中，3例出现光过敏反应，另外3例出现光加重反应。我们的结果表明，银胶菊皮炎的临床模式在发病后会发生显著变化，即从空气传播性接触性皮炎进展为混合型或CAD型。
