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系统性硬化症伴不寻常的脂膜炎及类似盘状红斑狼疮的覆盖性皮损。

Systemic sclerosis with unusual panniculitis and overlying discoid lupus erythematosus-like lesions.

作者信息

Oka Hiroshi, Tanikawa Akiko, Matsuda Fumio, Tanaka Masaru, Nishikawa Takeji

机构信息

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

出版信息

J Dtsch Dermatol Ges. 2005 Aug;3(8):627-9. doi: 10.1111/j.1610-0387.2005.05727.x.

Abstract

A 33-year-old men presented with systemic sclerosis accompanied by both unusual panniculitis and overlying discoid lupus erythematosus (DLE)-like skin changes on the left buttock. The lesion did not completely match either lupus erythematosus profundus or morphea profunda but featured clinical and pathological findings halfway between the two entities. No case report of co-existence of systemic sclerosis and morphea profunda was found in the literature, but there are three case reports of patients with systemic sclerosis and lupus erythematosus profundus. One of the three cases had DLE-like changes on the surface of the lesion, a clinical picture similar to our case. We speculated that the DLE-like changes in the overlying skin were due to local tissue ischemia. The accompanying panniculitis in our case was considered to be unique and somehow different from morphea profunda or lupus erythematosus profundus.

摘要

一名33岁男性患者,患有系统性硬化症,同时左侧臀部出现罕见的脂膜炎以及类似盘状红斑狼疮(DLE)的皮肤改变。该病变不完全符合深部红斑狼疮或深部硬斑病,但具有介于这两种疾病之间的临床和病理表现。文献中未发现系统性硬化症与深部硬斑病并存的病例报告,但有3例系统性硬化症与深部红斑狼疮患者的病例报告。这3例中的1例在病变表面有类似DLE的改变,临床表现与我们的病例相似。我们推测,病变上方皮肤类似DLE的改变是由于局部组织缺血所致。我们病例中伴随的脂膜炎被认为是独特的,在某种程度上不同于深部硬斑病或深部红斑狼疮。

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