Bhatia Vishal, Wilding Gregory E, Dhindsa Gurkiran, Bhatia Ruchi, Garg Rajesh K, Bonner Anthony J, Dhindsa Sandeep
Department of Internal Medicine, Mercy Hospital of Buffalo, NY 14220, USA.
Endocr Pract. 2004 Nov-Dec;10(6):467-71. doi: 10.4158/EP.10.6.467.
To establish a relationship between the control of blood glucose levels and the severity of congestive heart failure (CHF) in a retrospective review of medical records of patients with diabetes admitted with acute exacerbation of CHF and to assess the potential correlation between the number of days of hospitalization and the baseline and in-hospital glycemic status.
Medical records were reviewed to identify patients with diabetes admitted to a tertiary care center with exacerbation of CHF. Patients in whom any new complications developed that could have prolonged the hospitalization were excluded from the study. The number of days of hospitalization attributable to CHF were noted and statistically correlated with the glycemic control.
Data on 100 patients included in the study are presented. The duration of hospitalization ranged from 1 day to 2 weeks (mean, 4.79 +/- 3.03 days). The in-hospital glycemic control strongly correlated positively with the number of days of hospitalization (r = 0.499; 95% confidence interval [CI], 0.325 to 0.643). The admission blood glucose level also showed a strong positive correlation with the days of hospitalization (r = 0.587; 95% CI, 0.426 to 0.720). The mean hemoglobin A1c (HbA1c) correlated positively with the number of days in the hospital (r = 0.653; 95% CI, 0.508 to 0.764). The 51 patients with uncontrolled diabetes (HbA1c >7%) were hospitalized for a mean period of 6.3 +/- 3.2 days, in comparison with a mean duration of 3.2 +/- 1.9 days for the 49 patients with good outpatient glycemic control (HbA1c < or =7%).
Patients with diabetes admitted with exacerbation of CHF who have poor baseline or in-hospital glycemic control have a prolonged hospitalization.
通过对因充血性心力衰竭（CHF）急性加重而入院的糖尿病患者病历进行回顾性分析，建立血糖水平控制与CHF严重程度之间的关系，并评估住院天数与基线及住院期间血糖状态之间的潜在相关性。
查阅病历以确定在三级医疗中心因CHF加重而入院的糖尿病患者。排除出现任何可能延长住院时间的新并发症的患者。记录因CHF导致的住院天数，并与血糖控制情况进行统计学关联分析。
呈现了纳入研究的100例患者的数据。住院时间从1天到2周不等（平均为4.79±3.03天）。住院期间的血糖控制与住院天数呈显著正相关（r = 0.499；95%置信区间[CI]为0.325至0.643）。入院血糖水平与住院天数也呈显著正相关（r = 0.587；95%CI为0.426至0.720）。平均糖化血红蛋白（HbA1c）与住院天数呈正相关（r = 0.653；95%CI为0.508至0.764）。51例血糖控制不佳（HbA1c>7%）的糖尿病患者平均住院时间为6.3±3.2天，相比之下，49例门诊血糖控制良好（HbA1c≤7%）的患者平均住院时间为3.2±1.9天。
因CHF加重而入院的糖尿病患者，若基线或住院期间血糖控制不佳，则住院时间会延长。
