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在埃塞俄比亚东部公立医院,2 型糖尿病患者的住院、再入院和住院时间的幅度和预测因素:一项回顾性队列研究。

Magnitude and predictors of hospital admission, readmission, and length of stay among patients with type 2 diabetes at public hospitals of Eastern Ethiopia: a retrospective cohort study.

机构信息

Department of Epidemiology and Biostatistics, College of Health and Medical Sciences, Haramaya University, P. O. Box 135, Dire Dawa, Ethiopia.

出版信息

BMC Endocr Disord. 2021 Apr 19;21(1):74. doi: 10.1186/s12902-021-00744-3.

Abstract

BACKGROUND

Type 2 Diabetes (T2D) represents one of the leading causes for hospital admissions and outpatient visits. Hence, T2D continuously imposes a significant burden to healthcare systems. The aim of this study was to assess predictors of hospital admission, readmission rates, and length of hospital stay among T2D patients in government hospitals of Eastern Ethiopia from 2013 to 2017.

METHODS

This study utilized retrospective data from a cohort of T2D patients following their treatment in government hospitals in Harari regional state of Ethiopia. Predictor of hospital admission was determined using parametric survival analysis methods. The readmission rate and length of hospital stay were determined by Poisson regression and mixed effect Poisson regression, respectively. All association were performed at 95% confidence level. Significance of association with determinants was reported using the hazard rate for hospital admission, and the incidence rate for readmission and length of hospital stay. Optimal model for each outcome was selected by using information criteria after fitness was checked.

RESULTS

The hospital admission rate for T2D patients was 9.85 (95%CI: 8.32, 11.66) per 1000-person-year observation. Alcohol drinking, inactive lifestyle, being a rural resident, history of comorbidities, and experiencing chronic diabetes complications were predictors of hospital admission. Seventy-one (52.2%) of the admitted patients had a history of readmission. Readmission rate was increased by being female, duration of disease, inactive lifestyle, having BMI greater than 29.9 kg/m, and higher blood glucose. The median time of hospital stay for admitted patients was 18 (IQR:7). The length of hospital stay was longer among females, patients with the history of insulin administration, and higher blood glucose.

CONCLUSION

Multiple and complex factors were contributing for high diabetes admission and readmission rates as well as for longer in-hospital duration among T2D patients in Harari regional state. Socio-demographic characteristics (sex, place of residence), behavioral factors (alcohol intake, lifestyle), and medical conditions (longer duration of disease, comorbidities, chronic diabetes complications, higher blood glucose level, and treatment modality) were significant determinants of hospital admission, readmission and longer hospital stay among T2D patients.

摘要

背景

2 型糖尿病(T2D)是导致住院和门诊就诊的主要原因之一。因此,T2D 不断给医疗保健系统带来巨大负担。本研究旨在评估 2013 年至 2017 年期间埃塞俄比亚东部政府医院 T2D 患者住院、再入院率和住院时间的预测因素。

方法

本研究利用埃塞俄比亚哈拉里州政府医院治疗的 T2D 患者队列的回顾性数据。使用参数生存分析方法确定住院预测因素。再入院率和住院时间分别采用泊松回归和混合效应泊松回归确定。所有关联均在 95%置信水平下进行。使用住院入院率的危险比、再入院率和住院时间的发病率报告与决定因素的关联的显著性。通过检查拟合度后使用信息准则选择每个结果的最佳模型。

结果

T2D 患者的住院率为每 1000 人年观察 9.85(95%CI:8.32,11.66)。饮酒、不活跃的生活方式、农村居民、合并症史和慢性糖尿病并发症是住院的预测因素。71(52.2%)名入院患者有再入院史。女性、疾病持续时间、不活跃的生活方式、BMI 大于 29.9kg/m2和更高的血糖会增加再入院率。入院患者的中位住院时间为 18(IQR:7)。女性、接受胰岛素治疗的患者和更高血糖的患者住院时间更长。

结论

在哈拉里州,多种复杂因素导致 T2D 患者的糖尿病入院和再入院率较高,以及住院时间较长。社会人口学特征(性别、居住地)、行为因素(饮酒、生活方式)和医疗状况(疾病持续时间较长、合并症、慢性糖尿病并发症、血糖水平较高和治疗方式)是 T2D 患者住院、再入院和住院时间延长的重要决定因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ea/8054433/b06f20e68e9d/12902_2021_744_Fig1_HTML.jpg

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