Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
PLoS One. 2023 Oct 5;18(10):e0285142. doi: 10.1371/journal.pone.0285142. eCollection 2023.
Patients with heart failure (HF) are generally at higher risk of developing type 2 diabetes and having uncontrolled blood glucose. Furthermore, the prevalence of uncontrolled blood glucose in patients with HF is largely unknown. Identifying the factors associated with poor blood glucose control is a preliminary step in the development of effective intervention programs. The current cross-sectional study was conducted at two major hospitals to explore the factors associated with blood glucose control among patients with heart failure and type 2 diabetes. In addition to sociodemographic, medical records were used to collect medical information and a validated questionnaire was used to evaluate medication adherence. Regression analysis showed that poor medication adherence (OR = 0.432; 95%CI 0.204-0.912; P<0.05) and increased white blood cells count (OR = 1.12; 95%CI 1.033-1.213; P<0.01) were associated with poor glycemic control. For enhancing blood glucose control among patients with HF and diabetes, future intervention programs should specifically target patients who have high WBC counts and poor medication.
心力衰竭（HF）患者通常面临更高的 2 型糖尿病发病风险和血糖控制不佳的风险。此外，HF 患者血糖控制不佳的患病率在很大程度上尚不清楚。确定与血糖控制不良相关的因素是制定有效干预计划的初步步骤。本横断面研究在两家大医院进行，旨在探讨心力衰竭和 2 型糖尿病患者血糖控制相关因素。除了社会人口统计学因素外，还使用病历收集医疗信息，并使用经过验证的问卷评估药物依从性。回归分析表明，药物依从性差（OR=0.432；95%CI 0.204-0.912；P<0.05）和白细胞计数增加（OR=1.12；95%CI 1.033-1.213；P<0.01）与血糖控制不良相关。为了提高 HF 和糖尿病患者的血糖控制水平，未来的干预计划应特别针对白细胞计数高和药物依从性差的患者。
