MSRV/HERV-W/合胞素及其与多发性硬化症的关联：一种人类内源性逆转录病毒的可用性与危害性 - Suppr

Suppr

超能文献

MSRV/HERV-W/syncytin and its linkage to multiple sclerosis: the usability and the hazard of a human endogenous retrovirus.

作者信息

Dolei Antonina

机构信息

Department of Biomedical Sciences, University of Sassari, Sassari, Italy.

出版信息

J Neurovirol. 2005 Apr;11(2):232-5. doi: 10.1080/13550280590952899.

DOI:10.1080/13550280590952899

PMID:16036802

Abstract

摘要

相似文献

MSRV/HERV-W/syncytin and its linkage to multiple sclerosis: the usability and the hazard of a human endogenous retrovirus.MSRV/HERV-W/合胞素及其与多发性硬化症的关联：一种人类内源性逆转录病毒的可用性与危害性

J Neurovirol. 2005 Apr;11(2):232-5. doi: 10.1080/13550280590952899.

Expression and activation by Epstein Barr virus of human endogenous retroviruses-W in blood cells and astrocytes: inference for multiple sclerosis.人类内源性逆转录病毒-W 在血细胞和星形细胞中被 Epstein Barr 病毒表达和激活：多发性硬化症的推论。

PLoS One. 2012;7(9):e44991. doi: 10.1371/journal.pone.0044991. Epub 2012 Sep 27.

Human endogenous retroviruses in the aetiology of MS.人类内源性逆转录病毒在多发性硬化症发病机制中的作用。

Acta Neurol Scand. 2017 Nov;136 Suppl 201:18-21. doi: 10.1111/ane.12836.

Lack of immune responses against multiple sclerosis-associated retrovirus/human endogenous retrovirus W in patients with multiple sclerosis.多发性硬化症患者对多发性硬化症相关逆转录病毒/人类内源性逆转录病毒W缺乏免疫反应。

J Neurovirol. 2008 Apr;14(2):143-51. doi: 10.1080/13550280801958922.

Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences.转录的人类内源性逆转录病毒W env基因座分析阐明了多发性硬化症相关逆转录病毒env序列的起源。

Retrovirology. 2009 Apr 15;6:37. doi: 10.1186/1742-4690-6-37.

Human endogenous retroviruses and multiple sclerosis: innocent bystanders or disease determinants?人类内源性逆转录病毒与多发性硬化症：无辜旁观者还是疾病决定因素？

Biochim Biophys Acta. 2011 Feb;1812(2):162-76. doi: 10.1016/j.bbadis.2010.07.016. Epub 2010 Aug 6.

Expression and regulation of human endogenous retrovirus W elements.人类内源性逆转录病毒W元件的表达与调控

APMIS. 2016 Jan-Feb;124(1-2):52-66. doi: 10.1111/apm.12478.

Novel reliable real-time PCR for differential detection of MSRVenv and syncytin-1 in RNA and DNA from patients with multiple sclerosis.用于差异检测多发性硬化症患者RNA和DNA中MSRVenv和合体素-1的新型可靠实时PCR技术

J Virol Methods. 2009 Oct;161(1):98-106. doi: 10.1016/j.jviromet.2009.05.024. Epub 2009 Jun 6.

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis.脑损伤中的人类内源性逆转录病毒W：多发性硬化症靶向治疗的理论依据

Mult Scler Relat Disord. 2016 Jul;8:11-8. doi: 10.1016/j.msard.2016.04.006. Epub 2016 Apr 22.

Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6.多发性硬化症（MS）患者的大脑和外周血单核细胞过度表达与MS相关的逆转录病毒/HERV-W内源性逆转录病毒，但不表达人疱疹病毒6。

J Gen Virol. 2007 Jan;88(Pt 1):264-274. doi: 10.1099/vir.0.81890-0.

引用本文的文献

Epstein-Barr Virus Load Correlates with Multiple Sclerosis-Associated Retrovirus Envelope Expression.爱泼斯坦-巴尔病毒载量与多发性硬化症相关逆转录病毒包膜表达相关。

Biomedicines. 2022 Feb 5;10(2):387. doi: 10.3390/biomedicines10020387.

Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?人类内源性逆转录病毒是否会导致多发性硬化症，如果是，其作用机制是什么？

Mol Neurobiol. 2019 Apr;56(4):2590-2605. doi: 10.1007/s12035-018-1255-x. Epub 2018 Jul 25.

Infections and multiple sclerosis.感染与多发性硬化症

Handb Clin Neurol. 2014;122:151-71. doi: 10.1016/B978-0-444-52001-2.00007-8.

Human endogenous retroviral syncytin exerts inhibitory effect on invasive phenotype of B16F10 melanoma cells.人类内源性逆转录病毒合胞体蛋白对 B16F10 黑色素瘤细胞侵袭表型的抑制作用。

Chin J Cancer Res. 2013 Oct;25(5):556-64. doi: 10.3978/j.issn.1000-9604.2013.10.06.

Human endogenous retroviruses in multiple sclerosis: potential for novel neuro-pharmacological research.人类内源性逆转录病毒在多发性硬化症中的作用：新型神经药理学研究的潜力。

Curr Neuropharmacol. 2011 Jun;9(2):360-9. doi: 10.2174/157015911795596568.

Lipopolysaccharide stress induces cell-type specific production of murine leukemia virus type-endogenous retroviral virions in primary lymphoid cells.脂多糖应激诱导原代淋巴样细胞中鼠白血病病毒型内源性逆转录病毒病毒粒子的细胞类型特异性产生。

J Gen Virol. 2011 Feb;92(Pt 2):292-300. doi: 10.1099/vir.0.023416-0. Epub 2010 Oct 21.

Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders.肺炎衣原体感染及其在神经系统疾病中的作用。

Interdiscip Perspect Infect Dis. 2010;2010:273573. doi: 10.1155/2010/273573. Epub 2010 Feb 21.

Retrovirology. 2009 Apr 15;6:37. doi: 10.1186/1742-4690-6-37.

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease.多发性硬化症相关逆转录病毒及其内源性HERV-W家族：人类生理学和疾病中病毒学、遗传学和免疫学之间的生物学界面。

J Neurovirol. 2009 Jan;15(1):4-13. doi: 10.1080/13550280802448451. Epub 2008 Nov 26.

本文引用的文献

Correlation between disease severity and in vitro cytokine production mediated by MSRV (multiple sclerosis associated retroviral element) envelope protein in patients with multiple sclerosis.多发性硬化症患者疾病严重程度与由MSRV（多发性硬化症相关逆转录病毒元件）包膜蛋白介导的体外细胞因子产生之间的相关性。

J Neuroimmunol. 2005 Mar;160(1-2):195-203. doi: 10.1016/j.jneuroim.2004.10.019. Epub 2004 Dec 8.

Identification of endogenous retroviral reading frames in the human genome.人类基因组中内源性逆转录病毒阅读框的鉴定。

Retrovirology. 2004 Oct 11;1:32. doi: 10.1186/1742-4690-1-32.

Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.人类内源性逆转录病毒糖蛋白介导的氧化还原反应物诱导导致少突胶质细胞死亡和脱髓鞘。

Nat Neurosci. 2004 Oct;7(10):1088-95. doi: 10.1038/nn1319. Epub 2004 Sep 26.

The role of human endogenous retroviruses in trophoblast differentiation and placental development.人类内源性逆转录病毒在滋养层细胞分化和胎盘发育中的作用。

Placenta. 2004 Sep-Oct;25(8-9):673-83. doi: 10.1016/j.placenta.2004.02.008.

Simultaneous presence of endogenous retrovirus and herpes virus antigens has profound effect on cell-mediated immune responses: implications for multiple sclerosis.内源性逆转录病毒和疱疹病毒抗原的同时存在对细胞介导的免疫反应有深远影响：对多发性硬化症的启示。

AIDS Res Hum Retroviruses. 2004 Apr;20(4):415-23. doi: 10.1089/088922204323048168.

Expression and functions of human endogenous retroviruses in the placenta: an update.人类内源性逆转录病毒在胎盘中的表达及功能：最新进展

Placenta. 2004 Apr;25 Suppl A:S16-25. doi: 10.1016/j.placenta.2004.01.012.

In vitro modulation of the multiple sclerosis (MS)-associated retrovirus by cytokines: implications for MS pathogenesis.细胞因子对多发性硬化症（MS）相关逆转录病毒的体外调节作用：对MS发病机制的影响

J Neurovirol. 2003 Dec;9(6):637-43. doi: 10.1080/13550280390246462.

Mol Psychiatry. 2004 Jan;9(1):12-3. doi: 10.1038/sj.mp.4001439.

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.全基因组筛选融合性人类内源性逆转录病毒包膜蛋白，鉴定出了在灵长类进化过程中保守的基因——合体素2。

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13013-8. doi: 10.1073/pnas.2132646100. Epub 2003 Oct 13.

Multiple sclerosis-associated virus-related pol sequences found both in multiple sclerosis and healthy donors are more frequently expressed in multiple sclerosis patients.在多发性硬化症患者和健康供者中均发现的与多发性硬化症相关病毒有关的pol序列，在多发性硬化症患者中更频繁地表达。

J Neurovirol. 2003 Feb;9(1):112-7. doi: 10.1080/13550280390173355.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验