山竹子果实中的氧杂蒽酮和倍半萜衍生物。

Xanthone and sesquiterpene derivatives from the fruits of Garcinia scortechinii.

作者信息

Sukpondma Yaowapa, Rukachaisirikul Vatcharin, Phongpaichit Souwalak

机构信息

Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla, 90112, Thailand.

出版信息

J Nat Prod. 2005 Jul;68(7):1010-7. doi: 10.1021/np0580098.

DOI:10.1021/np0580098

PMID:16038540

Abstract

The fruits of Garcinia scortechinii afforded 10 new compounds: four caged-tetraprenylated xanthones (scortechinones Q-T, 1-4), four rearranged xanthones (scortechinones U-X, 5-8), and two sesquiterpene derivatives (scortechterpenes A, B, 9, 10), together with 14 known compounds: one sesquiterpene, two biflavonoids, and 11 caged-polyprenylated xanthones. Their structures were elucidated by analysis of spectroscopic data and comparison of the NMR data with those reported previously. All xanthone derivatives were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus.

摘要

斯氏藤黄的果实产生了10种新化合物：4种笼状四异戊烯基呫吨酮（斯氏藤黄酮Q - T，1 - 4）、4种重排呫吨酮（斯氏藤黄酮U - X，5 - 8）和2种倍半萜衍生物（斯氏藤黄萜A、B，9、10），以及14种已知化合物：1种倍半萜、2种双黄酮和11种笼状多异戊烯基呫吨酮。通过光谱数据分析以及将核磁共振数据与先前报道的数据进行比较来阐明它们的结构。对所有呫吨酮衍生物进行了抗耐甲氧西林金黄色葡萄球菌的抗菌活性评估。