华扁穗草茎中的黄酮类化合物。

Flavonoids from the stem of Eriophorum scheuchzeri.

作者信息

Maver Milena, Queiroz Emerson F, Wolfender Jean-Luc, Hostettmann Kurt

机构信息

Laboratoire de Pharmacognosie et Phytochimie, Section de Sciences Pharmaceutiques, University of Geneva, CH-1211 Geneva, Switzerland.

出版信息

J Nat Prod. 2005 Jul;68(7):1094-8. doi: 10.1021/np0580107.

DOI:10.1021/np0580107

PMID:16038557

Abstract

Activity-guided isolation of antifungal, antibacterial, and antioxidant compounds from the dichloromethane extract of the aerial parts of Eriophorum scheuchzeri led to the isolation of eight flavonoids. Three isoflavones and one flavanone are new natural compounds. The isolation of the bioactive compounds was performed by centrifugal partition chromatography. Fractions and pure compounds were monitored by a direct TLC bioautographic assay. Their structures were elucidated by spectroscopic and chemical methods.

摘要

通过活性导向从沼生羊胡子草地上部分的二氯甲烷提取物中分离抗真菌、抗菌和抗氧化化合物，得到了8种黄酮类化合物。其中三种异黄酮和一种黄烷酮是新的天然化合物。生物活性化合物的分离采用离心分配色谱法进行。通过直接薄层色谱生物自显影测定法监测各馏分和纯化合物。通过光谱和化学方法阐明了它们的结构。