Valsaraj R, Pushpangadan P, Smitt U W, Adsersen A, Christensen S B, Sittie A, Nyman U, Nielsen C, Olsen C E
Division of Ethnopharmacology, Tropical Botanic Garden and Research Institute, Kerala, India.
J Nat Prod. 1997 Jul;60(7):739-42. doi: 10.1021/np970010m.
A bioactivity-guided fractionation of an extract of Terminalia bellerica fruit rind led to the isolation of two new lignans named termilignan (1) and thannilignan (2), together with 7-hydroxy-3',4'-(methylenedioxy)flavan (3) and anolignan B (4). All four compounds possessed demonstrable anti-HIV-1, antimalarial, and antifungal activity in vitro.
对诃子果壳提取物进行生物活性导向的分级分离，得到了两种新的木脂素，分别命名为诃子木脂素（1）和番荔枝木脂素（2），以及7-羟基-3',4'-（亚甲二氧基）黄烷（3）和阿诺木脂素B（4）。所有这四种化合物在体外均具有明显的抗HIV-1、抗疟疾和抗真菌活性。
