Hatipoglu Ciğdem Ataman, Bilgin Gülden, Tulek Necla, Kosar Uğur
Department of Infectious Diseases and Clinical Microbiology, Ankara Training and Research Hospital, Dikimevi, Ankara 06340, Turkey.
J Infect. 2005 Aug;51(2):116-9. doi: 10.1016/j.jinf.2004.10.004. Epub 2004 Nov 11.
Pulmonary involvement is a rare manifestation of brucellosis. The aim of this study was to determine the incidence and forms of pulmonary involvement in the course of brucellosis.
A prospective study was carried out in 110 patients with brucellosis. All the patients were evaluated with their pulmonary symptoms, physical examination and chest radiography. If pulmonary pathologic findings were present, patients underwent additional diagnostic evaluations including computerized tomography of the thorax and pulmonary function tests.
From 110 patients, 11 (six females and five males) were diagnosed as pulmonary brucellosis. Eight of 11 patients had pulmonary symptoms including cough, sputum and dyspnoea. Radiologic findings were parenchymal nodules, lobar pneumonia, paratracheal lymphadenopathy and pleural effusion. At the end of the treatment of brucellosis, clinical findings of pulmonary involvement were recovered in all patients except four dyspnoeic patients who had coexisting COPD. Radiological findings were normal in three and improved in four patients after 6 months of the treatment.
Pulmonary involvement is a rare event in the course of brucellosis. But especially in endemic regions, brucellosis should never be forgotten as a causative agent in patients with pulmonary symptoms.
肺部受累是布鲁氏菌病的一种罕见表现。本研究的目的是确定布鲁氏菌病病程中肺部受累的发生率和形式。
对110例布鲁氏菌病患者进行了一项前瞻性研究。所有患者均接受了肺部症状、体格检查和胸部X线检查。如果存在肺部病理表现，患者接受了包括胸部计算机断层扫描和肺功能测试在内的额外诊断评估。
110例患者中，11例（6例女性和5例男性）被诊断为肺型布鲁氏菌病。11例患者中有8例有肺部症状，包括咳嗽、咳痰和呼吸困难。影像学表现为实质结节、大叶性肺炎、气管旁淋巴结肿大和胸腔积液。在布鲁氏菌病治疗结束时，除4例合并慢性阻塞性肺疾病的呼吸困难患者外，所有患者的肺部受累临床表现均恢复。治疗6个月后，3例患者影像学表现正常，4例患者有所改善。
肺部受累在布鲁氏菌病病程中是罕见事件。但特别是在流行地区，对于有肺部症状的患者，绝不能忘记布鲁氏菌病作为病因的可能性。
