Ortalo-Magné Annick, Culioli Gérald, Valls Robert, Pucci Bernard, Piovetti Louis
Laboratoire des Matériaux à Finalités Spécifiques (MFS), Equipe Chimie des Produits Naturels Marins, Université du Sud Toulon-Var, Avenue de l'Université, BP 20132, F-83957 La Garde cedex, France.
Phytochemistry. 2005 Oct;66(19):2316-23. doi: 10.1016/j.phytochem.2005.06.006.
From the lipophilic extract of the brown alga Bifurcaria bifurcata collected off the Atlantic coast of Southern Brittany (Quiberon, France), five polar linear diterpenoids have been isolated. These metabolites have been identified as hydroxylated derivatives of 13-oxo- and 13-hydroxygeranylgeraniol. Their structures were characterized on the basis of chemical and spectral evidence including two-dimensional NMR experiments and mass spectrometric techniques. The absolute configuration of the 13-position has been determined, for the 13-hydroxygeranylgeraniol derivatives, to be R by means of a modified Mosher's method and therefore that of 13-hydroxygeranylgeraniol (eleganediol) has been revised. Along with these compounds, three related known geranylgeraniol derivatives were also identified, and these data were used for chemotaxonomical purposes.
从采集于法国布列塔尼南部大西洋海岸（基伯龙）的叉状双叉藻的亲脂性提取物中，分离出了五种极性线性二萜类化合物。这些代谢产物已被鉴定为13-氧代-和13-羟基香叶基香叶醇的羟基化衍生物。它们的结构通过化学和光谱证据得以表征，包括二维核磁共振实验和质谱技术。借助改良的莫舍尔方法，已确定13-羟基香叶基香叶醇衍生物13位的绝对构型为R，因此13-羟基香叶基香叶醇（优雅二醇）的绝对构型也得到了修正。除了这些化合物外，还鉴定出了三种相关的已知香叶基香叶醇衍生物，这些数据被用于化学分类学目的。
