Preuss J, Dettmeyer R, Lignitz E, Madea B
Institute of Legal Medicine, University of Bonn, Stiftsplatz 12, D-53111 Bonn, Germany.
Forensic Sci Int. 2006 May 25;159(1):1-5. doi: 10.1016/j.forsciint.2005.06.001. Epub 2005 Jul 20.
Lipid-deposits in internal organs, e.g. nephrons, are discussed as reliable marker to determine hypothermia as cause of death. While investigations concerning lipid vacuoles in the epithelium of the renal tubules are already published, there is no systematic information available about hypothermia and lipid deposits in cardiomyocytes. Therefore, this retrospective study presents the first results of lipid-stainings of myocardial samples taken by autopsies in hypothermia-cases in comparison to samples from a control group. It was the aim of the study to clarify the conceivable causal relationship between death due to hypothermia and lipid-deposits apart from lipofuscin and fatty degeneration, respectively, in cardiomyocytes.
内脏器官(如肾单位)中的脂质沉积被视为确定低温为死因的可靠标志物。虽然有关肾小管上皮细胞中脂质空泡的研究已经发表,但关于低温与心肌细胞脂质沉积的系统性信息尚无报道。因此,本回顾性研究呈现了低温死亡病例尸检获取的心肌样本脂质染色的初步结果,并与对照组样本进行了比较。本研究旨在阐明低温致死与心肌细胞中除脂褐素和脂肪变性之外的脂质沉积之间可能存在的因果关系。