Johansen Jeanne D, Smith Else, Juel Knud, Rosdahl Nils
Department of Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
Scand J Public Health. 2005;33(3):222-7. doi: 10.1080/14034940510005671.
This study seeks to describe the impact of AIDS on the city of Copenhagen by estimating potential years of life lost (PYLL) before the age of 65 years and to estimate the impact of AIDS deaths on life expectancy for males and females.
All AIDS cases reported to the national AIDS surveillance register for residents in the city of Copenhagen in the period 1983-98 were included. For comparative purposes data were obtained on six other causes of death: accidents, suicide, lung cancer, ischaemic heart disease, testicular cancer, and breast cancer.
Overall, deaths from AIDS accounted for 8% of all PYLL in men and showed an increasing tendency from 1983 to 1991, when it became the leading cause of PYLL. AIDS had most impact in men in the age group 25-44 years and accounted for 29% of all PYLL in this group at the peak in 1993, decreasing significantly after the introduction of anti-retroviral treatments to 5% of PYLL in 1998. Other leading causes of PYLL, accidents and suicide, also showed a decreasing tendency over the years, but of a much smaller magnitude than AIDS. The impact of AIDS in women was more modest. In the entire study period suicide, accidents, and breast cancer were the leading causes of PYLL in women. It was shown that AIDS deaths at the top of the epidemic in 1991-95 were responsible for a loss of 0.76 years in life expectancy for men and 0.08 years for women.
AIDS has had a considerable impact on potential years of life lost. A significant decline in AIDS deaths has been seen since 1995 with an effect on life expectancy for men in the city of Copenhagen.
本研究旨在通过估算65岁之前潜在的寿命损失年数（PYLL）来描述艾滋病对哥本哈根市的影响，并估算艾滋病死亡对男性和女性预期寿命的影响。
纳入1983年至1998年期间向国家艾滋病监测登记处报告的所有哥本哈根市居民艾滋病病例。为作比较，获取了其他六种死因的数据：事故、自杀、肺癌、缺血性心脏病、睾丸癌和乳腺癌。
总体而言，艾滋病死亡占男性所有PYLL的8%，且从1983年至1991年呈上升趋势，1991年时成为PYLL的首要原因。艾滋病对25至44岁年龄组的男性影响最大，在1993年达到峰值时占该组所有PYLL的29%，在引入抗逆转录病毒治疗后，到1998年大幅降至PYLL的5%。其他主要的PYLL原因，事故和自杀，这些年也呈下降趋势，但降幅远小于艾滋病。艾滋病对女性的影响较小。在整个研究期间，自杀、事故和乳腺癌是女性PYLL的主要原因。结果显示，1991年至1995年疫情高峰期的艾滋病死亡导致男性预期寿命损失0.76年，女性损失0.08年。
艾滋病对潜在寿命损失年数有相当大的影响。自1995年以来，艾滋病死亡人数显著下降，对哥本哈根市男性的预期寿命产生了影响。
