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艾滋病毒感染和艾滋病对不列颠哥伦比亚省及加拿大死亡率的影响。

Impact of HIV infection and AIDS on death rates in British Columbia and Canada.

作者信息

Hogg R S, Schechter M T, Montaner J S, Goldstone I, Craib K, O'Shaughnessy M V

机构信息

British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver.

出版信息

CMAJ. 1994 Mar 1;150(5):711-7.

Abstract

OBJECTIVE

To assess the impact of HIV infection and AIDS on death rates in British Columbia and Canada.

DESIGN

Descriptive, population-based study.

SETTING

British Columbia and Canada.

PATIENTS

All people for whom HIV infection or AIDS was listed as the underlying cause of death in Canada and all provinces from 1987 to 1991, as reported to Statistics Canada, and all people for whom HIV infection or AIDS was listed as the underlying or antecedent cause of death in British Columbia and Vancouver from 1987 to 1992, as reported to the Division of Vital Statistics, British Columbia Ministry of Health.

MAIN OUTCOME MEASURES

Age- and cause-specific patterns of death, and potential years of life lost (PYLLs) for men.

RESULTS

From 1987 to 1991 a total of 4189 deaths from HIV infection and AIDS (in 3941 males and 248 females) in Canada and 686 such deaths (in 671 males and 15 females) in British Columbia were reported to Statistics Canada. The rate of death from HIV infection and AIDS was 1.39 times higher (95% confidence interval [CI] 1.29 to 1.50) in British Columbia than in Canada as a whole and 1.95 times higher (95% CI 1.65 to 2.29) when HIV infection was associated with specified malignant neoplasms than with other related causes. The PYLLs from HIV infection and AIDS for men rose steadily in Canada, from 17,615 in 1987 to 38,735 in 1991; the latter is comparable to the PYLLs from stroke and colorectal cancer. In Vancouver the PYLLs from HIV infection and AIDS for men increased sharply from 1987 to 1992, surpassing the PYLLs from heart disease, malignant neoplasms and accidents.

CONCLUSIONS

From 1987 to 1991 the rate of death from HIV infection and AIDS in British Columbia was higher than the national average. In Vancouver HIV infection and AIDS have become the leading causes of premature death in men, exceeding heart disease, malignant neoplasms and accidents.

摘要

目的

评估艾滋病毒感染和艾滋病对不列颠哥伦比亚省及加拿大死亡率的影响。

设计

基于人群的描述性研究。

地点

不列颠哥伦比亚省和加拿大。

患者

据加拿大统计局报告,1987年至1991年期间,在加拿大及所有省份,所有将艾滋病毒感染或艾滋病列为潜在死因的人;以及据不列颠哥伦比亚省卫生部生命统计司报告,1987年至1992年期间,在不列颠哥伦比亚省和温哥华,所有将艾滋病毒感染或艾滋病列为潜在或先行死因的人。

主要观察指标

按年龄和死因分类的死亡模式,以及男性的潜在寿命损失年数(PYLLs)。

结果

1987年至1991年,加拿大共有4189例因艾滋病毒感染和艾滋病死亡(男性3941例,女性248例),据加拿大统计局报告,不列颠哥伦比亚省有686例此类死亡(男性671例,女性15例)。不列颠哥伦比亚省因艾滋病毒感染和艾滋病的死亡率比加拿大全国高出1.39倍(95%置信区间[CI]1.29至1.50),当艾滋病毒感染与特定恶性肿瘤相关时,比与其他相关原因高出1.95倍(95%CI 1.65至2.29)。在加拿大,男性因艾滋病毒感染和艾滋病导致的潜在寿命损失年数稳步上升,从1987年的17,615年增至1991年的38,735年;后者与中风和结直肠癌导致的潜在寿命损失年数相当。在温哥华,1987年至1992年期间,男性因艾滋病毒感染和艾滋病导致的潜在寿命损失年数急剧增加,超过了心脏病、恶性肿瘤和事故导致的潜在寿命损失年数。

结论

1987年至1991年,不列颠哥伦比亚省因艾滋病毒感染和艾滋病的死亡率高于全国平均水平。在温哥华,艾滋病毒感染和艾滋病已成为男性过早死亡的主要原因,超过了心脏病、恶性肿瘤和事故。

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