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[平卧呼吸-直立性低氧血症综合征、房间隔瘤及右半膈肌抬高伴经卵圆孔未闭的右向左分流]

[Platypnea-orthodeoxia syndrome, atrial septal aneurysm and right hemidiaphragmatic elevation with a right-to-left shunt through a patent foramen ovale].

作者信息

Lopez Gaston Osvaldo D, Calnevaro Oscar, Gallego Claudio, Bluguermann Jorge, Barbieri David, Granja Miguel, Mc Loughlin Diego, Malvino Eduardo

机构信息

División Terapia Intensiva, Policlínica Bancaria, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 2005;65(3):252-4.

PMID:16042138
Abstract

Platypnea-orthodeoxia is an uncommon syndrome of dyspnea and hypoxemia induced by upright position, which is subsequently relieved by recumbency. The case reported involved a 75-year-old man with a seven days history of dyspnea in the upright position. The chest radiograph and CT scan demonstrated an elevated right hemidiaphragm. A surface echocardiogram with saline solution showed a patent foramen ovale (PFO) and atrial septal aneurysm. A pulmonary arteriogram was performed showing no evidence of pulmonary embolism and normal pulmonary arterial pressures. Later, he also developed dyspnea in the supine position and a transesophageal echocardiogram with contrast demonstrated a large right to left shunt through a PFO. The closure by a catheter-deployed double-umbrella device caused an immediate improvement in the patient's oxygenation.

摘要

平卧呼吸-直立性低氧血症是一种由直立位诱发的、以呼吸困难和低氧血症为表现的罕见综合征,平卧后症状可缓解。报道的该病例为一名75岁男性,有7天直立位呼吸困难病史。胸部X线片和CT扫描显示右半膈抬高。经盐水负荷的体表超声心动图显示卵圆孔未闭(PFO)和房间隔瘤。肺动脉造影显示无肺栓塞证据且肺动脉压正常。后来,他仰卧位时也出现呼吸困难,经食管对比超声心动图显示通过PFO有大量右向左分流。通过导管置入双伞装置封堵后,患者的氧合情况立即得到改善。

相似文献

1
[Platypnea-orthodeoxia syndrome, atrial septal aneurysm and right hemidiaphragmatic elevation with a right-to-left shunt through a patent foramen ovale].[平卧呼吸-直立性低氧血症综合征、房间隔瘤及右半膈肌抬高伴经卵圆孔未闭的右向左分流]
Medicina (B Aires). 2005;65(3):252-4.
2
Platypnea-orthodeoxia syndrome in the right lateral decubitus position: a case report.右侧卧位时的平卧呼吸-直立性低氧血症综合征:一例报告
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Platypnea-orthodeoxia syndrome in the elderly treated by percutaneous patent foramen ovale closure: a case series and literature review.老年体位性呼吸困难-低氧血症综合征行经皮卵圆孔未闭封堵术治疗:病例系列及文献复习。
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The effect of patent foramen ovale closure in patients with platypnea-orthodeoxia syndrome.卵圆孔未闭封堵术对平卧呼吸-直立性低氧血症综合征患者的影响。
Catheter Cardiovasc Interv. 2015 Oct;86(4):701-7. doi: 10.1002/ccd.25953. Epub 2015 Jun 9.
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Percutaneous Intervention to Treat Platypnea-Orthodeoxia Syndrome: The Toronto Experience.经皮介入治疗固缩性低通气-直立性低氧血症综合征:多伦多经验。
JACC Cardiovasc Interv. 2016 Sep 26;9(18):1928-38. doi: 10.1016/j.jcin.2016.07.003.
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Platypnea-orthodeoxia induced by fenestrated atrial septal aneurysm.多孔型房间隔瘤诱发的平卧呼吸困难-直立性低氧血症
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Platypnea-Orthodeoxia Syndrome: To Shunt or Not to Shunt, That is the Question.平卧呼吸困难-直立性低氧血症综合征:是否存在分流,这是个问题。
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Platypnea-Orthodeoxia Syndrome: Diagnostic Challenge and the Importance of Heightened Clinical Suspicion.平卧呼吸-直立性低氧血症综合征:诊断挑战及提高临床怀疑度的重要性
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Treatment of Platypnea-Orthodeoxia Syndrome in a Patient with Normal Cardiac Hemodynamics: A Review of Mechanisms with Implications for Management.心脏血流动力学正常患者的平卧呼吸-直立性低氧血症综合征治疗:对管理有影响的机制综述
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引用本文的文献

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Tilting the balance: hemidiaphragm paralysis leading to right to left cardiac shunt.天平倾斜:半侧膈肌麻痹导致右向左心脏分流。
BMJ Case Rep. 2018 Dec 3;11(1):bcr2018227944. doi: 10.1136/bcr-2018-227944.
2
Symptomatic Patent Foramen Ovale with Hemidiaphragm Paralysis.伴有半膈麻痹的有症状卵圆孔未闭
Case Rep Pulmonol. 2017;2017:9848696. doi: 10.1155/2017/9848696. Epub 2017 Oct 16.
3
Platypnea-orthodeoxia syndrome in the right lateral decubitus position: a case report.右侧卧位时的平卧呼吸-直立性低氧血症综合征:一例报告
J Med Case Rep. 2017 Apr 12;11(1):109. doi: 10.1186/s13256-017-1267-6.