Di Luigi L, Romanelli F, Lenzi A
Unit of Endocrinology, Department of Human Movement and Sport Sciences, University Institute of Motor Sciences, Rome, Italy.
J Endocrinol Invest. 2005;28(3 Suppl):81-4.
Androgenic-anabolic steroids (AAS) is an official definition for all male sex steroid hormones, their synthetic derivatives and their active metabolites. AAS are drugs with specific therapeutic indications, yet they are popularly known because of their worldwide non-therapeutic use in a large number of healthy individuals. Doping with AAS has become so widespread in athletics that it affects the outcome of sports contests. Furthermore, AAS non-therapeutic use is increasing particularly among adolescents and females, becoming one of the main causes of iatrogenic diseases due to drug abuse. All physicians must be aware about the large diffusion and side effects related to AAS non-therapeutic use, in order to discover clinical signs of AAS abuse and/or to start adequate preventive and/or therapeutic actions.
雄激素-同化类固醇（AAS）是所有雄性甾体激素、其合成衍生物及其活性代谢物的官方定义。AAS是具有特定治疗适应症的药物，但因其在大量健康个体中的全球非治疗性使用而广为人知。在体育运动中，使用AAS进行兴奋剂检测已变得非常普遍，以至于影响了体育比赛的结果。此外，AAS的非治疗性使用正在增加，尤其是在青少年和女性中，成为药物滥用导致医源性疾病的主要原因之一。所有医生都必须了解与AAS非治疗性使用相关的广泛传播和副作用，以便发现AAS滥用的临床迹象和/或开始采取适当的预防和/或治疗措施。
