苏联橡胶生产中的致癌物。

Carcinogens in rubber production in the Soviet Union.

作者信息

Solionova L G, Smulevich V B, Turbin E V, Krivosheyeva L V, Plotnikov J V

机构信息

All-Union Cancer Research Center AMS USSR, Laboratory of Occupational Cancer, Moscow, Commonwealth of Independent States.

出版信息

Scand J Work Environ Health. 1992 Apr;18(2):120-3. doi: 10.5271/sjweh.1602.

DOI:10.5271/sjweh.1602

PMID:1604272

Abstract

In a preliminary phase of a broad research project on cancer among workers in a rubber footwear plant in Moscow, exposure to several known or potential carcinogens was assessed. There were high dust contents bearing both toxic substances and carcinogens. The highest concentrations of benzo[a]pyrene (500-14,400 micrograms) were found on the soot used as a filler, and the maximum N-dimethylnitrosamine (DMNA) level was measured in thiram (150-23,868 micrograms.kg-1). Air samples from the vulcanization process and the pressing of rubber goods showed BaP levels of up to 1.43 micrograms.m-3. In the work area where polyvinyl chloride was used, the mean vinyl chloride concentration was 0.21 (SE 0.06) mg.m-3. The mean value of the acrylonitrile concentrations in the workroom area was 0.19 (SE 0.07) mg.m-3. Very high levels of DMNA and N-diethylnitrosamine were measured in the preparatory shop in the winter.

摘要

在莫斯科一家橡胶鞋厂开展的一项关于工人癌症的广泛研究项目的初步阶段，对几种已知或潜在致癌物的接触情况进行了评估。存在含有有毒物质和致癌物的高粉尘含量。用作填料的烟灰中苯并[a]芘浓度最高（500 - 14400微克），福美双中N - 二甲基亚硝胺（DMNA）水平最高（150 - 23868微克·千克⁻¹）。硫化过程和橡胶制品压制过程的空气样本显示苯并[a]芘水平高达1.43微克·立方米⁻³。在使用聚氯乙烯的工作区域，氯乙烯平均浓度为0.21（标准误0.06）毫克·立方米⁻³。车间区域丙烯腈浓度平均值为0.19（标准误0.07）毫克·立方米⁻³。冬季在准备车间检测到非常高的DMNA和N - 二乙基亚硝胺水平。