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社会经济因素与青少年妊娠结局:新生儿死亡与新生儿期后死亡之间的差异?

Socioeconomic factors and adolescent pregnancy outcomes: distinctions between neonatal and post-neonatal deaths?

作者信息

Markovitz Barry P, Cook Rebeka, Flick Louise H, Leet Terry L

机构信息

Saint Louis University School of Public Health, St, Louis, Missouri, USA.

出版信息

BMC Public Health. 2005 Jul 25;5:79. doi: 10.1186/1471-2458-5-79.

Abstract

BACKGROUND

Young maternal age has long been associated with higher infant mortality rates, but the role of socioeconomic factors in this association has been controversial. We sought to investigate the relationships between infant mortality (distinguishing neonatal from post-neonatal deaths), socioeconomic status and maternal age in a large, retrospective cohort study.

METHODS

We conducted a population-based cohort study using linked birth-death certificate data for Missouri residents during 1997-1999. Infant mortality rates for all singleton births to adolescent women (12-17 years, n = 10,131; 18-19 years, n = 18,954) were compared to those for older women (20-35 years, n = 28,899). Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI) for all potential associations.

RESULTS

The risk of infant (OR 1.95, CI 1.54-2.48), neonatal (1.69, 1.24-2.31) and post-neonatal mortality (2.47, 1.70-3.59) were significantly higher for younger adolescent (12-17 years) than older (20-34 years) mothers. After adjusting for race, marital status, age-appropriate education level, parity, smoking status, prenatal care utilization, and poverty status (indicated by participation in WIC, food stamps or Medicaid), the risk of post-neonatal mortality (1.73, 1.14-2.64) but not neonatal mortality (1.43, 0.98-2.08) remained significant for younger adolescent mothers. There were no differences in neonatal or post-neonatal mortality risks for older adolescent (18-19 years) mothers.

CONCLUSION

Socioeconomic factors may largely explain the increased neonatal mortality risk among younger adolescent mothers but not the increase in post-neonatal mortality risk.

摘要

背景

年轻产妇长期以来一直与较高的婴儿死亡率相关,但社会经济因素在这种关联中的作用一直存在争议。我们试图在一项大型回顾性队列研究中调查婴儿死亡率(区分新生儿死亡和新生儿后期死亡)、社会经济地位与产妇年龄之间的关系。

方法

我们利用1997 - 1999年密苏里州居民的出生-死亡证明关联数据进行了一项基于人群的队列研究。将所有青春期女性(12 - 17岁,n = 10131;18 - 19岁,n = 18954)单胎出生的婴儿死亡率与年龄较大女性(20 - 35岁,n = 28899)的进行比较。采用逻辑回归估计所有潜在关联的调整优势比(OR)和95%置信区间(CI)。

结果

年龄较小的青春期女性(12 - 17岁)的母亲所生婴儿死亡(OR 1.95,CI 1.54 - 2.48)、新生儿死亡(1.69,1.24 - 2.31)和新生儿后期死亡(2.47,1.70 - 3.59)风险显著高于年龄较大(20 - 34岁)的母亲。在调整种族、婚姻状况、适龄教育水平、产次、吸烟状况、产前护理利用情况和贫困状况(通过参与妇女、婴儿和儿童营养补充计划、食品券计划或医疗补助计划来表明)后,年龄较小的青春期母亲的新生儿后期死亡风险(1.73,1.14 - 2.64)仍然显著,但新生儿死亡风险(1.43,0.98 - 2.08)不再显著。年龄较大的青春期女性(18 - 19岁)母亲的新生儿或新生儿后期死亡风险没有差异。

结论

社会经济因素可能在很大程度上解释了年龄较小的青春期母亲新生儿死亡风险增加的原因,但不能解释新生儿后期死亡风险增加的原因。

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