Frissora Christine L, Koch Kenneth L
Department of Medicine, The Weill Medical College of Cornell University, 520 E. 70th Street, Suite J-314, New York, NY 10021, USA.
Curr Gastroenterol Rep. 2005 Aug;7(4):264-71. doi: 10.1007/s11894-005-0018-9.
Irritable bowel syndrome (IBS) is one of several highly prevalent, multi-symptom gastrointestinal motility disorders that have a wide clinical spectrum and are associated with symptoms of gastrointestinal dysmotility and visceral hypersensitivity. Symptom overlap and comorbidity between IBS and other gastrointestinal motility disorders (eg, chronic constipation, functional dyspepsia, gastroesophageal reflux disease), with gastrointestinal disorders that are not related to motility (eg, celiac disease, lactose intolerance), and with somatic conditions (eg, fibromyalgia, chronic fatigue syndrome), are frequent. The clinical associations and pathophysiologic links between IBS and these disorders continue to be explored. This review discusses overlapping symptoms and comorbidity of IBS with select gastrointestinal and non-gastrointestinal disorders and attempts to identify commonalities among these conditions.
肠易激综合征（IBS）是几种高度常见的、多症状的胃肠动力障碍之一，其临床谱广泛，与胃肠动力障碍和内脏高敏感性症状相关。IBS与其他胃肠动力障碍（如慢性便秘、功能性消化不良、胃食管反流病）、与非动力性胃肠疾病（如乳糜泻、乳糖不耐受）以及与躯体疾病（如纤维肌痛、慢性疲劳综合征）之间的症状重叠和共病很常见。IBS与这些疾病之间的临床关联和病理生理联系仍在不断探索中。本综述讨论了IBS与特定胃肠和非胃肠疾病的重叠症状和共病情况，并试图确定这些疾病之间的共性。
