Liu Robert S H, Hammond George S, Mirzadegan Taraneh
Department of Chemistry, University of Hawaii, 2545 The Mall, Honolulu, HI 96822, USA.
Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10783-7. doi: 10.1073/pnas.0501665102. Epub 2005 Jul 25.
In this work, we examine how the reported dual decay processes of rhodopsin and binding site stereospecificity can be accounted for by the recently available crystal structure of rhodopsin. Arguments are presented for possible presence of two rhodopsin "rotamers" that fit within the binding cavity. Directed pathways of decay could account for the observed excited decay processes. We summarize evidence for the possible existence of two different ground-state configurations that give rise to two different excited species.
在这项工作中，我们研究了视紫红质报道的双衰变过程和结合位点立体特异性如何能由最近获得的视紫红质晶体结构来解释。提出了关于视紫红质两个“旋转异构体”可能存在于结合腔内的观点。衰变的定向途径可以解释观察到的激发衰变过程。我们总结了可能存在两种不同基态构型从而产生两种不同激发态物种的证据。
