Hauck E W, Bschleipfer T, Haag S M, Rohde V, Weidner W
Klinik und Poliklinik für Urologie und Kinderurologie, Justus-Liebig-Universität, Giessen.
Urologe A. 2005 Oct;44(10):1189-92, 1193-6. doi: 10.1007/s00120-005-0867-8.
The aim of this study was to evaluate the frequency and the assessment of the different conservative modalities of treatment in Peyronie's disease. A representative survey among 3187 German urologists was performed using a standardized questionnaire comprising currently used concepts of therapy, their efficacy, and their tolerability.
A total of 636 urologists participated in the study. Altogether they had treated 6019 patients with Peyronie's disease in 2003. The majority of urologists treated between 3 and 15 patients per year. The most frequent treatment modality was the administration of potassium paraaminobenzoate, followed by vitamin E and extracorporeal shock wave therapy. Other oral drugs and intralesional drug administrations were used considerably less frequently.
The most commonly used treatment modalities were assessed for the best results in terms of efficacy and tolerability. However, this outcome is contradictory to the few controlled studies regarding the efficacy of the different drugs.
The large number of patients treated demonstrates the importance of conservative therapy for Peyronie's disease. Therefore, it is unfortunate that no conservative treatment modality is currently available that cures the symptoms of this disorder in all patients affected.
本研究旨在评估佩罗尼氏病不同保守治疗方式的使用频率及疗效评估。采用标准化问卷对3187名德国泌尿科医生进行了一项代表性调查，问卷内容包括当前使用的治疗理念、疗效及其耐受性。
共有636名泌尿科医生参与了该研究。2003年，他们总共治疗了6019例佩罗尼氏病患者。大多数泌尿科医生每年治疗3至15名患者。最常用的治疗方式是服用对氨基苯甲酸钾，其次是维生素E和体外冲击波疗法。其他口服药物和病灶内给药的使用频率要低得多。
就疗效和耐受性而言，对最常用的治疗方式进行了最佳效果评估。然而，这一结果与关于不同药物疗效的少数对照研究相矛盾。
大量接受治疗的患者表明了保守治疗对佩罗尼氏病的重要性。因此，遗憾的是目前尚无一种保守治疗方式能治愈所有受影响患者的这种疾病症状。
