Donov M, Tsolova N
Khirurgiia (Sofiia). 2004;60(6):30-4.
The necrotizing soft tissue infection caused by anaerobic microorganisms or by mixed aerobic-anaerobic flora is one of the most severe infections in surgical practice with a mortality rate up to 75%. Of great importance for successful treatment are the early diagnosis followed by aggressive debridement and adequate antibacterial therapy. Depending on the studies of 358 isolates made in the Clinic of Septic Surgery, we specify the most often used antibiotics in cases of severe anaerobic surgical infection. It is established that the incidence of this severe infection is unpredictable and its spreading depends on the immune answer the concomitant illnesses and the previous undertaken surgeries of the patient.
由厌氧微生物或需氧-厌氧混合菌群引起的坏死性软组织感染是外科手术中最严重的感染之一，死亡率高达75%。对于成功治疗至关重要的是早期诊断，随后进行积极清创和适当的抗菌治疗。根据在脓毒症外科诊所对358株分离菌的研究，我们明确了严重厌氧性外科感染病例中最常用的抗生素。已确定这种严重感染的发生率不可预测，其传播取决于患者的免疫反应、伴随疾病和先前接受的手术。
