Ben Fatma Leila, Landolsi Amel, Chouchene Lotfi, Ghaha Rafika, Boughattas Hamida, Bibi Mohamed, Nouira Monia, Gharbi Olfa, Hochlef Makram, Aloulou Samir, Ben Ahmd Slim
Service de médecine carcinologique CHU. F. Hached Sousse.
Tunis Med. 2005 May;83(5):262-8.
The genetic bases of inherited predisposition to cancer are now established. The aim of our study is to value the knowledge, attitude and behavior of the general population about the inherited predisposition to cancer. Our study involved a population of 200 individuals. Without any history of cancer. The mean age of our population was 37.5 years (18 to 74 years). The education level was low in 62.5% of cases (illiterate or primary education). About knowledge: heredity was considered a predisposing factor to cancer by 42.5% of the respondents. About attitude: we noted a cancerophobia in 82% of cases. 86.5% of our respondents trought that an early diagnosis increased the chance of recovery. About behavior: 72.5% of the studied population wishd to know if they were predisposed to develop cancer. In case of pregnancy, 79% wished to know if the foetus wasa cancer gene predisposition carrier. 28% would keep this foetus in case of positive genetic testing. These results are encouraging to develop oncogenetic counselling in Tunisia.
癌症遗传易感性的基因基础现已明确。我们研究的目的是评估普通人群对癌症遗传易感性的认知、态度和行为。我们的研究涉及200名无癌症病史的个体。我们研究对象的平均年龄为37.5岁（18至74岁）。62.5%的研究对象教育水平较低（文盲或小学学历）。关于认知：42.5%的受访者认为遗传是癌症的一个诱发因素。关于态度：我们发现82%的研究对象存在恐癌心理。86.5%的受访者认为早期诊断能增加康复几率。关于行为：72.5%的研究人群希望知道自己是否有患癌倾向。在怀孕的情况下，79%的人希望知道胎儿是否是癌症基因易感性携带者。如果基因检测呈阳性，28%的人会保留这个胎儿。这些结果对于在突尼斯开展肿瘤遗传咨询是令人鼓舞的。
