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银屑病关节炎临床试验中的疗效指标。

Outcome measures in psoriatic arthritis clinical trials.

作者信息

Reddy Soumya M, Bingham III Clifton O

机构信息

Division of Rheumatology, New York University School of Medicine and Hospital for Joint Diseases, Peter D. Seligman Center for Advanced Therapeutics, 246 E. 20th St., Suite 101, New York, NY 10003, USA.

出版信息

Curr Rheumatol Rep. 2005 Aug;7(4):299-305. doi: 10.1007/s11926-005-0040-9.

Abstract

Outcome measures in psoriatic arthritis (PsA) have been primarily borrowed from the assessment of rheumatoid arthritis and ankylosing spondylitis, although several specific measures for PsA have been established. The advent of new therapeutic agents for the treatment of PsA has made the need for specific outcome measures for PsA more critical to evaluate the heterogeneous manifestations of this disease and features that are unique to its assessment. Several outcome measures have been validated for use in PsA clinical trials while others are being evaluated by groups such as The Group for Assessment of Psoriasis and Psoriatic Arthritis for future use in clinical trials.

摘要

银屑病关节炎(PsA)的疗效评估指标主要借鉴了类风湿关节炎和强直性脊柱炎的评估方法,不过也已经确立了一些针对PsA的特定指标。用于治疗PsA的新型治疗药物的出现,使得针对PsA制定特定的疗效评估指标对于评估该疾病的异质性表现及其评估中独有的特征变得更为关键。已有多项疗效评估指标在PsA临床试验中得到验证,而其他一些指标正由银屑病和银屑病关节炎评估小组等团队进行评估,以供未来在临床试验中使用。

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