Callender Valerie D, Young Cherie M, Haverstock Christina L, Carroll Christie L, Feldman Steven R
Callender Skin & Laser Center, 12164 Central Ave, Suite 225, Mitchellville, MD 20721, USA.
Cutis. 2005 Jun;75(6):317-21.
Acne keloidalis (AK) is a disease affecting primarily African American men. Topical steroids are a widely accepted treatment of AK; however, no studies have been published investigating their effectiveness. The purpose of this open-label study was to assess the efficacy and tolerability of clobetasol propionate 0.05% and betamethasone valerate 0.12% foams in the treatment of AK in 20 African American patients. These patients were treated for 8 to 12 weeks using a pulsed-dose regimen. We found topical clobetasol propionate foam to be effective in improving AK, and our patients found the foam vehicle to be cosmetically acceptable.
瘢痕疙瘩性痤疮（AK）是一种主要影响非裔美国男性的疾病。外用类固醇是一种被广泛接受的AK治疗方法；然而，尚未有研究发表来调查其有效性。这项开放标签研究的目的是评估0.05%丙酸氯倍他索和0.12%戊酸倍他米松泡沫剂治疗20名非裔美国患者AK的疗效和耐受性。这些患者采用脉冲给药方案治疗8至12周。我们发现外用丙酸氯倍他索泡沫剂对改善AK有效，并且我们的患者认为该泡沫剂型在美观上是可以接受的。
