Napier Johnathan A, Sayanova Olga
Crop Performance and Improvement Division, Rothamsted Research, Harpenden, Herts AL5 2JQ, UK.
Proc Nutr Soc. 2005 Aug;64(3):387-93. doi: 10.1079/pns2005447.
There is now considerable evidence of the importance of n-3 long-chain PUFA in human health and development. At the same time, the marine fish stocks that serve as the primary sources of these fatty acids are threatened by continued over-exploitation. Thus, there is an urgent need to provide a sustainable alternative source of the n-3 long-chain PUFA normally found in fish oils. The possibility of using transgenic plants genetically engineered to synthesise these important fatty acids has recently been demonstrated. The approaches taken to realise this outcome will be discussed, as will their prospects for providing a sustainable resource for the future.
目前有大量证据表明n-3长链多不饱和脂肪酸在人类健康与发育中具有重要作用。与此同时,作为这些脂肪酸主要来源的海洋鱼类种群正受到持续过度捕捞的威胁。因此,迫切需要提供一种可持续的替代来源,以获取通常存在于鱼油中的n-3长链多不饱和脂肪酸。最近已证明利用基因工程改造的转基因植物来合成这些重要脂肪酸的可能性。本文将讨论为实现这一成果所采取的方法,以及它们为未来提供可持续资源的前景。