Janko O, Seier J, Zazgornik J
II. Medizinischen Abteilung, Allgemeinen Krankenhauses der Stadt Linz.
Wien Med Wochenschr. 1992;142(4):78-81.
In a retrospective study the frequency of hypokalemia was investigated in a large group of hospitalized patients. In a period of 1 year 33,426 patients were hospitalized, of these 1,177 (3.52%) revealed serum potassium level of less than or equal to 3.0 mmol/l. On admission to the hospital 592 (50.3%) showed serum potassium levels within normal range and developed their hypokalemia in the hospital. A severe hypokalemia equal or lower 2.5 mmol/l was observed only in 0.54% of the patients. Hypokalemia was frequently associated with cardiovascular, gastrointestinal and urogenital diseases following by diabetes mellitus and polytraumas. The main causes of hypokalemia were diuretics and gastrointestinal potassium loss. Severe hypokalemia (less than or equal to 2.5 mmol/l) is a predisposing factor for the occurrence of ectopic ventricular activity in patients with preexisting myocardial lesions like left ventricular hypertrophy or after myocardial infarction. Therefore in patients with preexisting myocardial lesions and severe hypokalemia potassium replacement therapy may be needed.
在一项回顾性研究中,对一大群住院患者的低钾血症发生率进行了调查。在1年的时间里,有33426名患者住院,其中1177名(3.52%)的血清钾水平低于或等于3.0 mmol/L。入院时,592名(50.3%)患者的血清钾水平在正常范围内,且在住院期间出现低钾血症。仅0.54%的患者观察到严重低钾血症,即血清钾水平等于或低于2.5 mmol/L。低钾血症常与心血管、胃肠道和泌尿生殖系统疾病相关,其次是糖尿病和多发伤。低钾血症的主要原因是利尿剂和胃肠道钾流失。严重低钾血症(小于或等于2.5 mmol/L)是已有心肌病变(如左心室肥厚)的患者或心肌梗死后发生室性异位活动的一个诱发因素。因此,对于已有心肌病变且有严重低钾血症的患者,可能需要进行补钾治疗。