Salyani Asif, Birt Catherine
Department of Ophthalmology and Vision Sciences, University of Toronto, Ont.
Can J Ophthalmol. 2005 Apr;40(2):170-4. doi: 10.1016/S0008-4182(05)80028-6.
Methods to improve patient compliance with prescribed topical use of glaucoma medication are sorely needed. A guide for the topical administration of ocular medication was suggested as such a tool. We investigated whether eye drop self-administration would be improved with use of the guide.
An eye drop guide, a funnel-shaped device designed to fit within the contour of the orbital margins, was offered to 114 patients for use at home with their glaucoma medication. A questionnaire asking about the ease of eye drop self-administration was administered before and after 1 week's use of the device.
Of the 111 patients who accepted the guide, 93 returned a usable completed questionnaire. Seventy-four percent said that they found it easier to administer their eye drops without the guide and preferred to do so (chi2 = 21.77, p < 0.01). Patients using more doses per day found it more difficult to administer their drops using the guide (r = -0.233, p < 0.05), and those who had been using drops longer preferred not to continue using the guide (r = -0.222, p < 0.05). Patients who found the written instructions clearer found it easier to administer their drops using the guide (r = 0.329, p < 0.05).
Although intended to ease the administration of eye drops, the guide proved to be counterproductive. Further work is necessary to investigate other methods of improving patient compliance with prescribed topical use of ocular medications.
目前亟需改善患者遵医嘱局部使用青光眼药物的方法。有人建议使用眼部药物局部给药指南作为这样一种工具。我们研究了使用该指南是否会改善滴眼剂的自我给药情况。
向114例患者提供了一种滴眼剂指南,这是一种设计成能贴合眼眶边缘轮廓的漏斗形装置,供他们在家中用于青光眼药物治疗。在使用该装置1周前后,发放了一份关于滴眼剂自我给药难易程度的问卷。
在接受该指南的111例患者中,93例返回了可用的完整问卷。74%的患者表示,他们发现不使用该指南滴眼更容易,且更愿意这样做(χ² = 21.77,p < 0.01)。每天使用滴眼剂剂量较多的患者发现使用该指南滴眼更困难(r = -0.233,p < 0.05),而使用滴眼剂时间较长的患者则更不愿意继续使用该指南(r = -0.222,p < 0.05)。认为书面说明更清晰的患者发现使用该指南滴眼更容易(r = 0.329,p < 0.05)。
尽管该指南旨在方便滴眼剂给药,但事实证明它适得其反。有必要进一步研究其他改善患者遵医嘱局部使用眼部药物的方法。